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Page 1
Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation.
Bergström P, Agholme L, Nazir FH, Satir TM, Toombs J, Wellington H, Strandberg J, Bontell TO, Kvartsberg H, Holmström M, Boreström C, Simonsson S, Kunath T, Lindahl A, Blennow K, Hanse E, Portelius E, Wray S, Zetterberg H. Bergström P, et al. Among authors: wellington h. Sci Rep. 2016 Jul 7;6:29200. doi: 10.1038/srep29200. Sci Rep. 2016. PMID: 27383650 Free PMC article.
Amyloid β peptides are differentially vulnerable to preanalytical surface exposure, an effect incompletely mitigated by the use of ratios.
Toombs J, Foiani MS, Wellington H, Paterson RW, Arber C, Heslegrave A, Lunn MP, Schott JM, Wray S, Zetterberg H. Toombs J, et al. Among authors: wellington h. Alzheimers Dement (Amst). 2018 Mar 22;10:311-321. doi: 10.1016/j.dadm.2018.02.005. eCollection 2018. Alzheimers Dement (Amst). 2018. PMID: 29780875 Free PMC article.
Increased CSF neurogranin concentration is specific to Alzheimer disease.
Wellington H, Paterson RW, Portelius E, Törnqvist U, Magdalinou N, Fox NC, Blennow K, Schott JM, Zetterberg H. Wellington H, et al. Neurology. 2016 Mar 1;86(9):829-35. doi: 10.1212/WNL.0000000000002423. Epub 2016 Jan 29. Neurology. 2016. PMID: 26826204 Free PMC article.
CSF neurogranin or tau distinguish typical and atypical Alzheimer disease.
Wellington H, Paterson RW, Suárez-González A, Poole T, Frost C, Sjöbom U, Slattery CF, Magdalinou NK, Lehmann M, Portelius E, Fox NC, Blennow K, Zetterberg H, Schott JM. Wellington H, et al. Ann Clin Transl Neurol. 2018 Jan 11;5(2):162-171. doi: 10.1002/acn3.518. eCollection 2018 Feb. Ann Clin Transl Neurol. 2018. PMID: 29468177 Free PMC article.
Concordance of CSF measures of Alzheimer's pathology with amyloid PET status in a preclinical cohort: A comparison of Lumipulse and established immunoassays.
Keshavan A, Wellington H, Chen Z, Khatun A, Chapman M, Hart M, Cash DM, Coath W, Parker TD, Buchanan SM, Keuss SE, Harris MJ, Murray-Smith H, Heslegrave A, Fox NC, Zetterberg H, Schott JM. Keshavan A, et al. Among authors: wellington h. Alzheimers Dement (Amst). 2020 Sep 13;12(1):e12097. doi: 10.1002/dad2.12097. eCollection 2020. Alzheimers Dement (Amst). 2020. PMID: 32999915 Free PMC article.
Concordance of CSF measures of Alzheimer's pathology with amyloid PET status in a preclinical cohort: A comparison of Lumipulse and established immunoassays.
Keshavan A, Wellington H, Chen Z, Khatun A, Chapman M, Hart M, Cash DM, Coath W, Parker TD, Buchanan SM, Keuss SE, Harris MJ, Murray-Smith H, Heslegrave A, Fox NC, Zetterberg H, Schott JM. Keshavan A, et al. Among authors: wellington h. Alzheimers Dement (Amst). 2021 Feb 6;13(1):e12131. doi: 10.1002/dad2.12131. eCollection 2021. Alzheimers Dement (Amst). 2021. PMID: 33598527 Free PMC article.
Assessing Neurofilaments as Biomarkers of Neuroprotection in Progressive Multiple Sclerosis: From the MS-STAT Randomized Controlled Trial.
Williams TE, Holdsworth KP, Nicholas JM, Eshaghi A, Katsanouli T, Wellington H, Heslegrave A, Zetterberg H, Frost C, Chataway J. Williams TE, et al. Among authors: wellington h. Neurol Neuroimmunol Neuroinflamm. 2022 Jan 14;9(2):e1130. doi: 10.1212/NXI.0000000000001130. Print 2022 Mar. Neurol Neuroimmunol Neuroinflamm. 2022. PMID: 35031587 Free PMC article. Clinical Trial.
Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study.
Wagen AZ, Coath W, Keshavan A, James SN, Parker TD, Lane CA, Buchanan SM, Keuss SE, Storey M, Lu K, Macdougall A, Murray-Smith H, Freiberger T, Cash DM, Malone IB, Barnes J, Sudre CH, Wong A, Pavisic IM, Street R, Crutch SJ, Escott-Price V, Leonenko G, Zetterberg H, Wellington H, Heslegrave A, Barkhof F, Richards M, Fox NC, Cole JH, Schott JM. Wagen AZ, et al. Among authors: wellington h. Lancet Healthy Longev. 2022 Sep;3(9):e607-e616. doi: 10.1016/S2666-7568(22)00167-2. Epub 2022 Aug 22. Lancet Healthy Longev. 2022. PMID: 36102775 Free PMC article.
Serum neurofilament light and MRI predictors of cognitive decline in patients with secondary progressive multiple sclerosis: Analysis from the MS-STAT randomised controlled trial.
Williams T, Tur C, Eshaghi A, Doshi A, Chan D, Binks S, Wellington H, Heslegrave A, Zetterberg H, Chataway J. Williams T, et al. Among authors: wellington h. Mult Scler. 2022 Oct;28(12):1913-1926. doi: 10.1177/13524585221114441. Epub 2022 Aug 9. Mult Scler. 2022. PMID: 35946107 Free PMC article. Clinical Trial.
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