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Inhibitors of ORAI1 Prevent Cytosolic Calcium-Associated Injury of Human Pancreatic Acinar Cells and Acute Pancreatitis in 3 Mouse Models.
Wen L, Voronina S, Javed MA, Awais M, Szatmary P, Latawiec D, Chvanov M, Collier D, Huang W, Barrett J, Begg M, Stauderman K, Roos J, Grigoryev S, Ramos S, Rogers E, Whitten J, Velicelebi G, Dunn M, Tepikin AV, Criddle DN, Sutton R. Wen L, et al. Gastroenterology. 2015 Aug;149(2):481-92.e7. doi: 10.1053/j.gastro.2015.04.015. Epub 2015 Apr 25. Gastroenterology. 2015. PMID: 25917787 Free PMC article.
Novel lipophilic probe for detecting near-membrane reactive oxygen species responses and its application for studies of pancreatic acinar cells: effects of pyocyanin and L-ornithine.
Chvanov M, Huang W, Jin T, Wen L, Armstrong J, Elliot V, Alston B, Burdyga A, Criddle DN, Sutton R, Tepikin AV. Chvanov M, et al. Among authors: wen l. Antioxid Redox Signal. 2015 Feb 20;22(6):451-64. doi: 10.1089/ars.2013.5589. Epub 2014 Apr 30. Antioxid Redox Signal. 2015. PMID: 24635199 Free PMC article.
Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP.
Mukherjee R, Mareninova OA, Odinokova IV, Huang W, Murphy J, Chvanov M, Javed MA, Wen L, Booth DM, Cane MC, Awais M, Gavillet B, Pruss RM, Schaller S, Molkentin JD, Tepikin AV, Petersen OH, Pandol SJ, Gukovsky I, Criddle DN, Gukovskaya AS, Sutton R; NIHR Pancreas Biomedical Research Unit. Mukherjee R, et al. Among authors: wen l. Gut. 2016 Aug;65(8):1333-46. doi: 10.1136/gutjnl-2014-308553. Epub 2015 Jun 12. Gut. 2016. PMID: 26071131 Free PMC article.
Caffeine protects against experimental acute pancreatitis by inhibition of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release.
Huang W, Cane MC, Mukherjee R, Szatmary P, Zhang X, Elliott V, Ouyang Y, Chvanov M, Latawiec D, Wen L, Booth DM, Haynes AC, Petersen OH, Tepikin AV, Criddle DN, Sutton R. Huang W, et al. Among authors: wen l. Gut. 2017 Feb;66(2):301-313. doi: 10.1136/gutjnl-2015-309363. Epub 2015 Dec 7. Gut. 2017. PMID: 26642860 Free PMC article.
4,696 results