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Distinct contributions of hyperglycemia and high-fat feeding in metabolic syndrome-induced neuroinflammation.
Wanrooy BJ, Kumar KP, Wen SW, Qin CX, Ritchie RH, Wong CHY. Wanrooy BJ, et al. J Neuroinflammation. 2018 Oct 22;15(1):293. doi: 10.1186/s12974-018-1329-8. J Neuroinflammation. 2018. PMID: 30348168 Free PMC article.
METHODS: Male C57Bl/6 J adult mice were treated with either citrate vehicle (CIT) or streptozotocin (STZ; 55 mg/kg) 3, 5 and 7 days before commencement of either a normal or high-fat diet for 9 or 18 weeks. By creating separate models of high-fat feeding, STZ-induced hyper …
METHODS: Male C57Bl/6 J adult mice were treated with either citrate vehicle (CIT) or streptozotocin (STZ; 55 mg/kg) 3, 5 and 7 days before c …