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Metabolomics assessment reveals oxidative stress and altered energy production in the heart after ischemic acute kidney injury in mice.
Fox BM, Gil HW, Kirkbride-Romeo L, Bagchi RA, Wennersten SA, Haefner KR, Skrypnyk NI, Brown CN, Soranno DE, Gist KM, Griffin BR, Jovanovich A, Reisz JA, Wither MJ, D'Alessandro A, Edelstein CL, Clendenen N, McKinsey TA, Altmann C, Faubel S. Fox BM, et al. Among authors: wennersten sa. Kidney Int. 2019 Mar;95(3):590-610. doi: 10.1016/j.kint.2018.10.020. Epub 2019 Jan 30. Kidney Int. 2019. PMID: 30709662 Free PMC article.
Female and male mice have differential longterm cardiorenal outcomes following a matched degree of ischemia-reperfusion acute kidney injury.
Soranno DE, Baker P 2nd, Kirkbride-Romeo L, Wennersten SA, Ding K, Keith B, Cavasin MA, Altmann C, Bagchi RA, Haefner KR, Montford J, Gist KM, Vergnes L, Reue K, He Z, Elajaili H, Okamura K, Nozik E, McKinsey TA, Faubel S. Soranno DE, et al. Among authors: wennersten sa. Sci Rep. 2022 Jan 12;12(1):643. doi: 10.1038/s41598-021-04701-x. Sci Rep. 2022. PMID: 35022484 Free PMC article.
Acute Kidney Injury Results in Long-Term Diastolic Dysfunction That Is Prevented by Histone Deacetylase Inhibition.
Soranno DE, Kirkbride-Romeo L, Wennersten SA, Ding K, Cavasin MA, Baker P, Altmann C, Bagchi RA, Haefner KR, Steinkühler C, Montford JR, Keith B, Gist KM, McKinsey TA, Faubel S. Soranno DE, et al. Among authors: wennersten sa. JACC Basic Transl Sci. 2021 Feb 22;6(2):119-133. doi: 10.1016/j.jacbts.2020.11.013. eCollection 2021 Feb. JACC Basic Transl Sci. 2021. PMID: 33665513 Free PMC article.
HDAC Inhibition Reverses Preexisting Diastolic Dysfunction and Blocks Covert Extracellular Matrix Remodeling.
Travers JG, Wennersten SA, Peña B, Bagchi RA, Smith HE, Hirsch RA, Vanderlinden LA, Lin YH, Dobrinskikh E, Demos-Davies KM, Cavasin MA, Mestroni L, Steinkühler C, Lin CY, Houser SR, Woulfe KC, Lam MPY, McKinsey TA. Travers JG, et al. Among authors: wennersten sa. Circulation. 2021 May 11;143(19):1874-1890. doi: 10.1161/CIRCULATIONAHA.120.046462. Epub 2021 Mar 8. Circulation. 2021. PMID: 33682427 Free PMC article.
HDAC6 modulates myofibril stiffness and diastolic function of the heart.
Lin YH, Major JL, Liebner T, Hourani Z, Travers JG, Wennersten SA, Haefner KR, Cavasin MA, Wilson CE, Jeong MY, Han Y, Gotthardt M, Ferguson SK, Ambardekar AV, Lam MP, Choudhary C, Granzier HL, Woulfe KC, McKinsey TA. Lin YH, et al. Among authors: wennersten sa. J Clin Invest. 2022 May 16;132(10):e148333. doi: 10.1172/JCI148333. J Clin Invest. 2022. PMID: 35575093 Free PMC article.
Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism.
Jeong MY, Lin YH, Wennersten SA, Demos-Davies KM, Cavasin MA, Mahaffey JH, Monzani V, Saripalli C, Mascagni P, Reece TB, Ambardekar AV, Granzier HL, Dinarello CA, McKinsey TA. Jeong MY, et al. Among authors: wennersten sa. Sci Transl Med. 2018 Feb 7;10(427):eaao0144. doi: 10.1126/scitranslmed.aao0144. Sci Transl Med. 2018. PMID: 29437146 Free PMC article.
DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy.
Ferguson BS, Wennersten SA, Demos-Davies KM, Rubino M, Robinson EL, Cavasin MA, Stratton MS, Kidger AM, Hu T, Keyse SM, McKnight RA, Lane RH, Nozik ES, Weiser-Evans MCM, McKinsey TA. Ferguson BS, et al. Among authors: wennersten sa. Am J Physiol Heart Circ Physiol. 2021 Aug 1;321(2):H382-H389. doi: 10.1152/ajpheart.00115.2021. Epub 2021 Jun 18. Am J Physiol Heart Circ Physiol. 2021. PMID: 34142888 Free PMC article.
A high-stringency blueprint of the human proteome.
Adhikari S, Nice EC, Deutsch EW, Lane L, Omenn GS, Pennington SR, Paik YK, Overall CM, Corrales FJ, Cristea IM, Van Eyk JE, Uhlén M, Lindskog C, Chan DW, Bairoch A, Waddington JC, Justice JL, LaBaer J, Rodriguez H, He F, Kostrzewa M, Ping P, Gundry RL, Stewart P, Srivastava S, Srivastava S, Nogueira FCS, Domont GB, Vandenbrouck Y, Lam MPY, Wennersten S, Vizcaino JA, Wilkins M, Schwenk JM, Lundberg E, Bandeira N, Marko-Varga G, Weintraub ST, Pineau C, Kusebauch U, Moritz RL, Ahn SB, Palmblad M, Snyder MP, Aebersold R, Baker MS. Adhikari S, et al. Nat Commun. 2020 Oct 16;11(1):5301. doi: 10.1038/s41467-020-19045-9. Nat Commun. 2020. PMID: 33067450 Free PMC article. Review.
13 results