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Pre-clinical validation of a novel alpha-7 nicotinic receptor radiotracer, [(3)H]AZ11637326: target localization, biodistribution and ligand occupancy in the rat brain.
Maier DL, Hill G, Ding M, Tuke D, Einstein E, Gurley D, Gordon JC, Bock MJ, Smith JS, Bialecki R, Eisman M, Elmore CS, Werkheiser JL. Maier DL, et al. Among authors: werkheiser jl. Neuropharmacology. 2011 Jul-Aug;61(1-2):161-71. doi: 10.1016/j.neuropharm.2011.03.024. Epub 2011 Apr 7. Neuropharmacology. 2011. PMID: 21497612
Ultra-low exposure to α-7 nicotinic acetylcholine receptor partial agonists elicits an improvement in cognition that corresponds with an increase in α-7 receptor expression in rodents: implications for low dose clinical efficacy.
Werkheiser JL, Sydserff S, Hubbs SJ, Ding M, Eisman MS, Perry D, Williams AJ, Smith JS, Mrzljak L, Maier DL. Werkheiser JL, et al. Neuroscience. 2011 Jul 14;186:76-87. doi: 10.1016/j.neuroscience.2011.04.033. Epub 2011 Apr 24. Neuroscience. 2011. PMID: 21550383
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