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A20: from ubiquitin editing to tumour suppression.
Hymowitz SG, Wertz IE. Hymowitz SG, et al. Among authors: wertz ie. Nat Rev Cancer. 2010 May;10(5):332-41. doi: 10.1038/nrc2775. Epub 2010 Apr 12. Nat Rev Cancer. 2010. PMID: 20383180 Review.
Ubiquitin-mediated regulation of TNFR1 signaling.
Wertz IE, Dixit VM. Wertz IE, et al. Cytokine Growth Factor Rev. 2008 Jun-Aug;19(3-4):313-24. doi: 10.1016/j.cytogfr.2008.04.014. Epub 2008 Jun 2. Cytokine Growth Factor Rev. 2008. PMID: 18515172 Review.
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Newton K, Matsumoto ML, Wertz IE, Kirkpatrick DS, Lill JR, Tan J, Dugger D, Gordon N, Sidhu SS, Fellouse FA, Komuves L, French DM, Ferrando RE, Lam C, Compaan D, Yu C, Bosanac I, Hymowitz SG, Kelley RF, Dixit VM. Newton K, et al. Among authors: wertz ie. Cell. 2008 Aug 22;134(4):668-78. doi: 10.1016/j.cell.2008.07.039. Cell. 2008. PMID: 18724939 Free article.
Ubiquitin binding to A20 ZnF4 is required for modulation of NF-κB signaling.
Bosanac I, Wertz IE, Pan B, Yu C, Kusam S, Lam C, Phu L, Phung Q, Maurer B, Arnott D, Kirkpatrick DS, Dixit VM, Hymowitz SG. Bosanac I, et al. Among authors: wertz ie. Mol Cell. 2010 Nov 24;40(4):548-57. doi: 10.1016/j.molcel.2010.10.009. Mol Cell. 2010. PMID: 21095585 Free article.
Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
Wertz IE, Kusam S, Lam C, Okamoto T, Sandoval W, Anderson DJ, Helgason E, Ernst JA, Eby M, Liu J, Belmont LD, Kaminker JS, O'Rourke KM, Pujara K, Kohli PB, Johnson AR, Chiu ML, Lill JR, Jackson PK, Fairbrother WJ, Seshagiri S, Ludlam MJ, Leong KG, Dueber EC, Maecker H, Huang DC, Dixit VM. Wertz IE, et al. Nature. 2011 Mar 3;471(7336):110-4. doi: 10.1038/nature09779. Nature. 2011. PMID: 21368834
COP1 is a tumour suppressor that causes degradation of ETS transcription factors.
Vitari AC, Leong KG, Newton K, Yee C, O'Rourke K, Liu J, Phu L, Vij R, Ferrando R, Couto SS, Mohan S, Pandita A, Hongo JA, Arnott D, Wertz IE, Gao WQ, French DM, Dixit VM. Vitari AC, et al. Among authors: wertz ie. Nature. 2011 May 15;474(7351):403-6. doi: 10.1038/nature10005. Nature. 2011. PMID: 21572435
61 results