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Excess Rab4 rescues synaptic and behavioral dysfunction caused by defective HTT-Rab4 axonal transport in Huntington's disease.
Acta Neuropathol Commun. 2020 Jul 1;8(1):97. doi: 10.1186/s40478-020-00964-z.
Acta Neuropathol Commun. 2020.
PMID: 32611447
Free PMC article.
In Vivo Visualization of Moving Synaptic Cargo Complexes within Drosophila Larval Segmental Axons.
Banerjee R, White JA 2nd, Gunawardena S.
Banerjee R, et al. Among authors: white ja 2nd.
Methods Mol Biol. 2020;2143:293-300. doi: 10.1007/978-1-0716-0585-1_21.
Methods Mol Biol. 2020.
PMID: 32524488
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Excess active P13K rescues huntingtin-mediated neuronal cell death but has no effect on axonal transport defects.
Hansen T, Thant C, White JA 2nd, Banerjee R, Thuamsang B, Gunawardena S.
Hansen T, et al. Among authors: white ja 2nd.
Apoptosis. 2019 Apr;24(3-4):341-358. doi: 10.1007/s10495-019-01520-4.
Apoptosis. 2019.
PMID: 30725352
Free PMC article.
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Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration.
Xu W, Weissmiller AM, White JA 2nd, Fang F, Wang X, Wu Y, Pearn ML, Zhao X, Sawa M, Chen S, Gunawardena S, Ding J, Mobley WC, Wu C.
Xu W, et al. Among authors: white ja 2nd.
J Clin Invest. 2016 May 2;126(5):1815-33. doi: 10.1172/JCI82409. Epub 2016 Apr 11.
J Clin Invest. 2016.
PMID: 27064279
Free PMC article.
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Huntingtin differentially regulates the axonal transport of a sub-set of Rab-containing vesicles in vivo.
White JA 2nd, Anderson E, Zimmerman K, Zheng KH, Rouhani R, Gunawardena S.
White JA 2nd, et al.
Hum Mol Genet. 2015 Dec 20;24(25):7182-95. doi: 10.1093/hmg/ddv415. Epub 2015 Oct 8.
Hum Mol Genet. 2015.
PMID: 26450517
Free PMC article.
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Presenilin influences glycogen synthase kinase-3 β (GSK-3β) for kinesin-1 and dynein function during axonal transport.
Dolma K, Iacobucci GJ, Hong Zheng K, Shandilya J, Toska E, White JA 2nd, Spina E, Gunawardena S.
Dolma K, et al. Among authors: white ja 2nd.
Hum Mol Genet. 2014 Mar 1;23(5):1121-33. doi: 10.1093/hmg/ddt505. Epub 2013 Oct 8.
Hum Mol Genet. 2014.
PMID: 24105467
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