White KL - Search Results

1

Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists.

Claff T, Yu J, Blais V, Patel N, Martin C, Wu L, Han GW, Holleran BJ, Van der Poorten O, White KL, Hanson MA, Sarret P, Gendron L, Cherezov V, Katritch V, Ballet S, Liu ZJ, Müller CE, Stevens RC. Claff T, et al. Among authors: white kl. Sci Adv. 2019 Nov 27;5(11):eaax9115. doi: 10.1126/sciadv.aax9115. eCollection 2019 Nov. Sci Adv. 2019. PMID: 31807708 Free PMC article.

2

NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptor.

O'Connor C, White KL, Doncescu N, Didenko T, Roth BL, Czaplicki G, Stevens RC, Wüthrich K, Milon A. O'Connor C, et al. Among authors: white kl. Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11852-7. doi: 10.1073/pnas.1510117112. Epub 2015 Sep 8. Proc Natl Acad Sci U S A. 2015. PMID: 26372966 Free PMC article.

3

Single-molecule view of basal activity and activation mechanisms of the G protein-coupled receptor β2AR.

Lamichhane R, Liu JJ, Pljevaljcic G, White KL, van der Schans E, Katritch V, Stevens RC, Wüthrich K, Millar DP. Lamichhane R, et al. Among authors: white kl. Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):14254-9. doi: 10.1073/pnas.1519626112. Epub 2015 Nov 2. Proc Natl Acad Sci U S A. 2015. PMID: 26578769 Free PMC article.

4

Structural basis for selectivity and diversity in angiotensin II receptors.

Zhang H, Han GW, Batyuk A, Ishchenko A, White KL, Patel N, Sadybekov A, Zamlynny B, Rudd MT, Hollenstein K, Tolstikova A, White TA, Hunter MS, Weierstall U, Liu W, Babaoglu K, Moore EL, Katz RD, Shipman JM, Garcia-Calvo M, Sharma S, Sheth P, Soisson SM, Stevens RC, Katritch V, Cherezov V. Zhang H, et al. Among authors: white ta, white kl. Nature. 2017 Apr 20;544(7650):327-332. doi: 10.1038/nature22035. Epub 2017 Apr 5. Nature. 2017. PMID: 28379944 Free PMC article.

5

Allosteric Coupling of Drug Binding and Intracellular Signaling in the A_2A Adenosine Receptor.

Eddy MT, Lee MY, Gao ZG, White KL, Didenko T, Horst R, Audet M, Stanczak P, McClary KM, Han GW, Jacobson KA, Stevens RC, Wüthrich K. Eddy MT, et al. Among authors: white kl. Cell. 2018 Jan 11;172(1-2):68-80.e12. doi: 10.1016/j.cell.2017.12.004. Epub 2017 Dec 28. Cell. 2018. PMID: 29290469 Free PMC article.

6

Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling.

White KL, Eddy MT, Gao ZG, Han GW, Lian T, Deary A, Patel N, Jacobson KA, Katritch V, Stevens RC. White KL, et al. Structure. 2018 Feb 6;26(2):259-269.e5. doi: 10.1016/j.str.2017.12.013. Epub 2018 Jan 27. Structure. 2018. PMID: 29395784 Free PMC article.

7

Opportunities and Challenges in Building a Spatiotemporal Multi-scale Model of the Human Pancreatic β Cell.

Singla J, McClary KM, White KL, Alber F, Sali A, Stevens RC. Singla J, et al. Among authors: white kl. Cell. 2018 Mar 22;173(1):11-19. doi: 10.1016/j.cell.2018.03.014. Cell. 2018. PMID: 29570991 Free PMC article. Review.

8

Crystal structure of misoprostol bound to the labor inducer prostaglandin E₂ receptor.

Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, Katritch V, Cherezov V, Hanson MA, Stevens RC. Audet M, et al. Among authors: white kl. Nat Chem Biol. 2019 Jan;15(1):11-17. doi: 10.1038/s41589-018-0160-y. Epub 2018 Dec 3. Nat Chem Biol. 2019. PMID: 30510194 Free PMC article.

9

Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E₂ receptor.

Audet M, White KL, Breton B, Zarzycka B, Han GW, Lu Y, Gati C, Batyuk A, Popov P, Velasquez J, Manahan D, Hu H, Weierstall U, Liu W, Shui W, Katritch V, Cherezov V, Hanson MA, Stevens RC. Audet M, et al. Among authors: white kl. Nat Chem Biol. 2019 Feb;15(2):206. doi: 10.1038/s41589-018-0214-1. Nat Chem Biol. 2019. PMID: 30573766

10

The lipid phase preference of the adenosine A_2A receptor depends on its ligand binding state.

Gutierrez MG , Deyell J , White KL , Dalle Ore LC , Cherezov V , Stevens RC , Malmstadt N . Gutierrez MG , et al. Among authors: white kl. Chem Commun (Camb). 2019 May 14;55(40):5724-5727. doi: 10.1039/c8cc10130b. Chem Commun (Camb). 2019. PMID: 31038495 Free PMC article.

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