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Targeting intracellular nontuberculous mycobacteria and M. tuberculosis with a bactericidal enzymatic cocktail.
Microbiol Spectr. 2024 May 2;12(5):e0353423. doi: 10.1128/spectrum.03534-23. Epub 2024 Mar 27.
Microbiol Spectr. 2024.
PMID: 38534149
Free PMC article.
Ex vivo and in vivo evidence that cigarette smoke-exposed T regulatory cells impair host immunity against Mycobacterium tuberculosis.
Bai X, Verma D, Garcia C, Musheyev A, Kim K, Fornis L, Griffith DE, Li L, Whittel N, Gadwa J, Ohanjanyan T, Eggleston MJ, Galvan M, Freed BM, Ordway D, Chan ED.
Bai X, et al. Among authors: whittel n.
Front Cell Infect Microbiol. 2023 Oct 26;13:1216492. doi: 10.3389/fcimb.2023.1216492. eCollection 2023.
Front Cell Infect Microbiol. 2023.
PMID: 37965256
Free PMC article.
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Therapeutic efficacy of antimalarial drugs targeting DosRS signaling in Mycobacterium abscessus.
Belardinelli JM, Verma D, Li W, Avanzi C, Wiersma CJ, Williams JT, Johnson BK, Zimmerman M, Whittel N, Angala B, Wang H, Jones V, Dartois V, de Moura VCN, Gonzalez-Juarrero M, Pearce C, Schenkel AR, Malcolm KC, Nick JA, Charman SA, Wells TNC, Podell BK, Vennerstrom JL, Ordway DJ, Abramovitch RB, Jackson M.
Belardinelli JM, et al. Among authors: whittel n.
Sci Transl Med. 2022 Feb 23;14(633):eabj3860. doi: 10.1126/scitranslmed.abj3860. Epub 2022 Feb 23.
Sci Transl Med. 2022.
PMID: 35196022
Free PMC article.
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Apramycin Overcomes the Inherent Lack of Antimicrobial Bactericidal Activity in Mycobacterium abscessus.
Selchow P, Ordway DJ, Verma D, Whittel N, Petrig A, Hobbie SN, Böttger EC, Sander P.
Selchow P, et al. Among authors: whittel n.
Antimicrob Agents Chemother. 2022 Feb 15;66(2):e0151021. doi: 10.1128/AAC.01510-21. Epub 2021 Dec 20.
Antimicrob Agents Chemother. 2022.
PMID: 34930031
Free PMC article.
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