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Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease.
Schäffner E, Bosch-Queralt M, Edgar JM, Lehning M, Strauß J, Fleischer N, Kungl T, Wieghofer P, Berghoff SA, Reinert T, Krueger M, Morawski M, Möbius W, Barrantes-Freer A, Stieler J, Sun T, Saher G, Schwab MH, Wrede C, Frosch M, Prinz M, Reich DS, Flügel A, Stadelmann C, Fledrich R, Nave KA, Stassart RM. Schäffner E, et al. Among authors: wieghofer p. Nat Neurosci. 2023 Jul;26(7):1218-1228. doi: 10.1038/s41593-023-01366-9. Epub 2023 Jun 29. Nat Neurosci. 2023. PMID: 37386131 Free PMC article.
Genetic targeting of microglia.
Wieghofer P, Knobeloch KP, Prinz M. Wieghofer P, et al. Glia. 2015 Jan;63(1):1-22. doi: 10.1002/glia.22727. Epub 2014 Aug 8. Glia. 2015. PMID: 25132502 Review.
Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways.
Kierdorf K, Erny D, Goldmann T, Sander V, Schulz C, Perdiguero EG, Wieghofer P, Heinrich A, Riemke P, Hölscher C, Müller DN, Luckow B, Brocker T, Debowski K, Fritz G, Opdenakker G, Diefenbach A, Biber K, Heikenwalder M, Geissmann F, Rosenbauer F, Prinz M. Kierdorf K, et al. Among authors: wieghofer p. Nat Neurosci. 2013 Mar;16(3):273-80. doi: 10.1038/nn.3318. Epub 2013 Jan 20. Nat Neurosci. 2013. PMID: 23334579
Origin, fate and dynamics of macrophages at central nervous system interfaces.
Goldmann T, Wieghofer P, Jordão MJ, Prutek F, Hagemeyer N, Frenzel K, Amann L, Staszewski O, Kierdorf K, Krueger M, Locatelli G, Hochgerner H, Zeiser R, Epelman S, Geissmann F, Priller J, Rossi FM, Bechmann I, Kerschensteiner M, Linnarsson S, Jung S, Prinz M. Goldmann T, et al. Among authors: wieghofer p. Nat Immunol. 2016 Jul;17(7):797-805. doi: 10.1038/ni.3423. Epub 2016 May 2. Nat Immunol. 2016. PMID: 27135602 Free PMC article.
Host microbiota constantly control maturation and function of microglia in the CNS.
Erny D, Hrabě de Angelis AL, Jaitin D, Wieghofer P, Staszewski O, David E, Keren-Shaul H, Mahlakoiv T, Jakobshagen K, Buch T, Schwierzeck V, Utermöhlen O, Chun E, Garrett WS, McCoy KD, Diefenbach A, Staeheli P, Stecher B, Amit I, Prinz M. Erny D, et al. Among authors: wieghofer p. Nat Neurosci. 2015 Jul;18(7):965-77. doi: 10.1038/nn.4030. Epub 2015 Jun 1. Nat Neurosci. 2015. PMID: 26030851 Free PMC article.
A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation.
Voet S, Mc Guire C, Hagemeyer N, Martens A, Schroeder A, Wieghofer P, Daems C, Staszewski O, Vande Walle L, Jordao MJC, Sze M, Vikkula HK, Demeestere D, Van Imschoot G, Scott CL, Hoste E, Gonçalves A, Guilliams M, Lippens S, Libert C, Vandenbroucke RE, Kim KW, Jung S, Callaerts-Vegh Z, Callaerts P, de Wit J, Lamkanfi M, Prinz M, van Loo G. Voet S, et al. Among authors: wieghofer p. Nat Commun. 2018 May 23;9(1):2036. doi: 10.1038/s41467-018-04376-5. Nat Commun. 2018. PMID: 29789522 Free PMC article.
36 results