Wierling C - Search Results

1

A framework for validating AI in precision medicine: considerations from the European ITFoC consortium.

Tsopra R, Fernandez X, Luchinat C, Alberghina L, Lehrach H, Vanoni M, Dreher F, Sezerman OU, Cuggia M, de Tayrac M, Miklasevics E, Itu LM, Geanta M, Ogilvie L, Godey F, Boldisor CN, Campillo-Gimenez B, Cioroboiu C, Ciusdel CF, Coman S, Hijano Cubelos O, Itu A, Lange B, Le Gallo M, Lespagnol A, Mauri G, Soykam HO, Rance B, Turano P, Tenori L, Vignoli A, Wierling C, Benhabiles N, Burgun A. Tsopra R, et al. Among authors: wierling c. BMC Med Inform Decis Mak. 2021 Oct 2;21(1):274. doi: 10.1186/s12911-021-01634-3. BMC Med Inform Decis Mak. 2021. PMID: 34600518 Free PMC article.

2

Network and systems biology: essential steps in virtualising drug discovery and development.

Wierling C, Kessler T, Ogilvie LA, Lange BM, Yaspo ML, Lehrach H. Wierling C, et al. Drug Discov Today Technol. 2015 Aug;15:33-40. doi: 10.1016/j.ddtec.2015.07.002. Epub 2015 Aug 8. Drug Discov Today Technol. 2015. PMID: 26464088 Review.

3

Predictive Modeling of Drug Treatment in the Area of Personalized Medicine.

Ogilvie LA, Wierling C, Kessler T, Lehrach H, Lange BMH. Ogilvie LA, et al. Among authors: wierling c. Cancer Inform. 2015 Dec 6;14(Suppl 4):95-103. doi: 10.4137/CIN.S1933. eCollection 2015. Cancer Inform. 2015. PMID: 26692759 Free PMC article.

4

Models of Models: A Translational Route for Cancer Treatment and Drug Development.

Ogilvie LA, Kovachev A, Wierling C, Lange BMH, Lehrach H. Ogilvie LA, et al. Among authors: wierling c. Front Oncol. 2017 Sep 19;7:219. doi: 10.3389/fonc.2017.00219. eCollection 2017. Front Oncol. 2017. PMID: 28971064 Free PMC article.

5

Effect of Linearization in a WNT Signaling Model.

Ciușdel CF, Coman S, Boldișor C, Kessler T, Muradyan A, Kovachev A, Lehrach H, Wierling C, Itu LM. Ciușdel CF, et al. Among authors: wierling c. Comput Math Methods Med. 2019 Jun 10;2019:8461820. doi: 10.1155/2019/8461820. eCollection 2019. Comput Math Methods Med. 2019. PMID: 31281412 Free PMC article.

6

Resources, standards and tools for systems biology.

Wierling C, Herwig R, Lehrach H. Wierling C, et al. Brief Funct Genomic Proteomic. 2007 Sep;6(3):240-51. doi: 10.1093/bfgp/elm027. Epub 2007 Oct 17. Brief Funct Genomic Proteomic. 2007. PMID: 17942476

7

ConsensusPathDB--a database for integrating human functional interaction networks.

Kamburov A, Wierling C, Lehrach H, Herwig R. Kamburov A, et al. Among authors: wierling c. Nucleic Acids Res. 2009 Jan;37(Database issue):D623-8. doi: 10.1093/nar/gkn698. Epub 2008 Oct 21. Nucleic Acids Res. 2009. PMID: 18940869 Free PMC article.

8

Modeling of miRNA and drug action in the EGFR signaling pathway.

Li J, Pandey V, Kessler T, Lehrach H, Wierling C. Li J, et al. Among authors: wierling c. PLoS One. 2012;7(1):e30140. doi: 10.1371/journal.pone.0030140. Epub 2012 Jan 11. PLoS One. 2012. PMID: 22253908 Free PMC article.

9

Mini-batch optimization enables training of ODE models on large-scale datasets.

Stapor P, Schmiester L, Wierling C, Merkt S, Pathirana D, Lange BMH, Weindl D, Hasenauer J. Stapor P, et al. Among authors: wierling c. Nat Commun. 2022 Jan 10;13(1):34. doi: 10.1038/s41467-021-27374-6. Nat Commun. 2022. PMID: 35013141 Free PMC article.

10

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H, Jang SH, Duarte JM, Wierling C, Lehrach H, Lappe M, Lange BM. Stehr H, et al. Among authors: wierling c. Mol Cancer. 2011 May 16;10:54. doi: 10.1186/1476-4598-10-54. Mol Cancer. 2011. PMID: 21575214 Free PMC article.

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