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Increased amphetamine-induced hyperactivity and reward in mice overexpressing the dopamine transporter.
Salahpour A, Ramsey AJ, Medvedev IO, Kile B, Sotnikova TD, Holmstrand E, Ghisi V, Nicholls PJ, Wong L, Murphy K, Sesack SR, Wightman RM, Gainetdinov RR, Caron MG. Salahpour A, et al. Among authors: wightman rm. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4405-10. doi: 10.1073/pnas.0707646105. Epub 2008 Mar 17. Proc Natl Acad Sci U S A. 2008. PMID: 18347339 Free PMC article.
Dopamine neuronal transport kinetics and effects of amphetamine.
Jones SR, Joseph JD, Barak LS, Caron MG, Wightman RM. Jones SR, et al. Among authors: wightman rm. J Neurochem. 1999 Dec;73(6):2406-14. doi: 10.1046/j.1471-4159.1999.0732406.x. J Neurochem. 1999. PMID: 10582600 Free article.
Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits.
Masoud ST, Vecchio LM, Bergeron Y, Hossain MM, Nguyen LT, Bermejo MK, Kile B, Sotnikova TD, Siesser WB, Gainetdinov RR, Wightman RM, Caron MG, Richardson JR, Miller GW, Ramsey AJ, Cyr M, Salahpour A. Masoud ST, et al. Among authors: wightman rm. Neurobiol Dis. 2015 Feb;74:66-75. doi: 10.1016/j.nbd.2014.10.016. Epub 2014 Oct 30. Neurobiol Dis. 2015. PMID: 25447236 Free PMC article.
301 results