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Showing results for Wild_guzman
Your search for Wild_Gunman retrieved no results
Mapping the human genetic architecture of COVID-19.
COVID-19 Host Genetics Initiative. COVID-19 Host Genetics Initiative. Nature. 2021 Dec;600(7889):472-477. doi: 10.1038/s41586-021-03767-x. Epub 2021 Jul 8. Nature. 2021. PMID: 34237774 Free PMC article.
Whole-genome sequencing reveals host factors underlying critical COVID-19.
Kousathanas A, Pairo-Castineira E, Rawlik K, Stuckey A, Odhams CA, Walker S, Russell CD, Malinauskas T, Wu Y, Millar J, Shen X, Elliott KS, Griffiths F, Oosthuyzen W, Morrice K, Keating S, Wang B, Rhodes D, Klaric L, Zechner M, Parkinson N, Siddiq A, Goddard P, Donovan S, Maslove D, Nichol A, Semple MG, Zainy T, Maleady-Crowe F, Todd L, Salehi S, Knight J, Elgar G, Chan G, Arumugam P, Patch C, Rendon A, Bentley D, Kingsley C, Kosmicki JA, Horowitz JE, Baras A, Abecasis GR, Ferreira MAR, Justice A, Mirshahi T, Oetjens M, Rader DJ, Ritchie MD, Verma A, Fowler TA, Shankar-Hari M, Summers C, Hinds C, Horby P, Ling L, McAuley D, Montgomery H, Openshaw PJM, Elliott P, Walsh T, Tenesa A; GenOMICC investigators; 23andMe investigators; COVID-19 Human Genetics Initiative; Fawkes A, Murphy L, Rowan K, Ponting CP, Vitart V, Wilson JF, Yang J, Bretherick AD, Scott RH, Hendry SC, Moutsianas L, Law A, Caulfield MJ, Baillie JK. Kousathanas A, et al. Nature. 2022 Jul;607(7917):97-103. doi: 10.1038/s41586-022-04576-6. Epub 2022 Mar 7. Nature. 2022. PMID: 35255492 Free PMC article.
Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection.
Sohail A, Iqbal AA, Sahini N, Chen F, Tantawy M, Waqas SFH, Winterhoff M, Ebensen T, Schultz K, Geffers R, Schughart K, Preusse M, Shehata M, Bähre H, Pils MC, Guzman CA, Mostafa A, Pleschka S, Falk C, Michelucci A, Pessler F. Sohail A, et al. PLoS Pathog. 2022 Jan 13;18(1):e1010219. doi: 10.1371/journal.ppat.1010219. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 35025971 Free PMC article.
In IAV-infected mice, pulmonary inflammation and weight loss were greater in Acod1-/- than in wild-type mice, and DI treatment reduced pulmonary inflammation and mortality. ...
In IAV-infected mice, pulmonary inflammation and weight loss were greater in Acod1-/- than in wild-type mice, and DI treatment reduce …
Li-Fraumeni Syndrome-Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death.
Choe JH, Kawase T, Xu A, Guzman A, Obradovic AZ, Low-Calle AM, Alaghebandan B, Raghavan A, Long K, Hwang PM, Schiffman JD, Zhu Y, Zhao R, Lee DF, Katz C, Prives C. Choe JH, et al. Cancer Discov. 2023 May 4;13(5):1250-1273. doi: 10.1158/2159-8290.CD-22-0882. Cancer Discov. 2023. PMID: 37067901 Free PMC article.
Here, we characterized the germline OD mutant p53(A347D), which occurs in cancer-prone Li-Fraumeni syndrome (LFS) patients. Unlike wild-type p53, mutant p53(A347D) cannot form tetramers and exists as a hyperstable dimeric protein. ...Thus, dimer-forming p53 demonstrates bo …
Here, we characterized the germline OD mutant p53(A347D), which occurs in cancer-prone Li-Fraumeni syndrome (LFS) patients. Unlike wild
Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators. Salloway S, et al. N Engl J Med. 2014 Jan 23;370(4):322-33. doi: 10.1056/NEJMoa1304839. N Engl J Med. 2014. PMID: 24450891 Free PMC article. Clinical Trial.
Monoallelic variation in DHX9, the gene encoding the DExH-box helicase DHX9, underlies neurodevelopment disorders and Charcot-Marie-Tooth disease.
Calame DG, Guo T, Wang C, Garrett L, Jolly A, Dawood M, Kurolap A, Henig NZ, Fatih JM, Herman I, Du H, Mitani T, Becker L, Rathkolb B, Gerlini R, Seisenberger C, Marschall S, Hunter JV, Gerard A, Heidlebaugh A, Challman T, Spillmann RC, Jhangiani SN, Coban-Akdemir Z, Lalani S, Liu L, Revah-Politi A, Iglesias A, Guzman E, Baugh E, Boddaert N, Rondeau S, Ormieres C, Barcia G, Tan QKG, Thiffault I, Pastinen T, Sheikh K, Biliciler S, Mei D, Melani F, Shashi V, Yaron Y, Steele M, Wakeling E, Østergaard E, Nazaryan-Petersen L; Undiagnosed Diseases Network; Millan F, Santiago-Sim T, Thevenon J, Bruel AL, Thauvin-Robinet C, Popp D, Platzer K, Gawlinski P, Wiszniewski W, Marafi D, Pehlivan D, Posey JE, Gibbs RA, Gailus-Durner V, Guerrini R, Fuchs H, Hrabě de Angelis M, Hölter SM, Cheung HH, Gu S, Lupski JR. Calame DG, et al. Am J Hum Genet. 2023 Aug 3;110(8):1394-1413. doi: 10.1016/j.ajhg.2023.06.013. Epub 2023 Jul 18. Am J Hum Genet. 2023. PMID: 37467750 Free PMC article.
We investigated DHX9 variant-associated cellular phenotypes in human cell lines. Whereas wild-type DHX9 was restricted to the nucleus, NLS missense variants abnormally accumulated in the cytoplasm. ...
We investigated DHX9 variant-associated cellular phenotypes in human cell lines. Whereas wild-type DHX9 was restricted to the nucleus …
Human-to-dog transmission of SARS-CoV-2, Colombia.
Rivero R, Garay E, Botero Y, Serrano-Coll H, Gastelbondo B, Muñoz M, Ballesteros N, Castañeda S, Patiño LH, Ramirez JD, Calderon A, Guzmán C, Martinez-Bravo C, Aleman A, Arrieta G, Mattar S. Rivero R, et al. Sci Rep. 2022 May 12;12(1):7880. doi: 10.1038/s41598-022-11847-9. Sci Rep. 2022. PMID: 35551247 Free PMC article.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of the current COVID-19 pandemic, has evolved to have a wide range of hosts, including non-human primates, wild and domestic animals. The ACE2 protein has a high level of conservation and is …
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of the current COVID-19 pandemic, has evolved to have a wi …
Vocalizations of wild West Indian manatee vary across subspecies and geographic location.
Reyes-Arias JD, Brady B, Ramos EA, Henaut Y, Castelblanco-Martínez DN, Maust-Mohl M, Searle L, Pérez-Lachaud G, Guzmán HM, Poveda H, Merchan F, Contreras K, Sanchez-Galan JE, Collom KA, Magnasco MO. Reyes-Arias JD, et al. Sci Rep. 2023 Jul 7;13(1):11028. doi: 10.1038/s41598-023-37882-8. Sci Rep. 2023. PMID: 37419931 Free PMC article.
Geographic variation in the vocal behavior of manatees has been reported but is largely unexplored. Vocalizations of wild West Indian manatees (Trichechus manatus) were recorded with hydrophones in Florida from Florida manatees (Trichechus manatus latirostris), and in Beli …
Geographic variation in the vocal behavior of manatees has been reported but is largely unexplored. Vocalizations of wild West Indian …
Nutritional and Bioactive Compounds in Mexican Lupin Beans Species: A Mini-Review.
Ruiz-López MA, Barrientos-Ramírez L, García-López PM, Valdés-Miramontes EH, Zamora-Natera JF, Rodríguez-Macias R, Salcedo-Pérez E, Bañuelos-Pineda J, Vargas-Radillo JJ. Ruiz-López MA, et al. Nutrients. 2019 Aug 2;11(8):1785. doi: 10.3390/nu11081785. Nutrients. 2019. PMID: 31382375 Free PMC article. Review.
As a source of bioactive compounds, species of the genus Lupinus are interesting legumes from a nutritional point of view. Although wild species are abundant and represent a potential source of nutrients and biologically active compounds, most research has focused on domes …
As a source of bioactive compounds, species of the genus Lupinus are interesting legumes from a nutritional point of view. Although wild
Molecular genotyping of Blastocystis spp. in wild mammals from Mexico.
Martinez-Hernandez F, Martinez-Ibarra JA, Lopez-Escamilla E, Villanueva-Garcia C, Muñoz-Garcia CI, Rendon-Franco E, Maravilla P, Villalobos G. Martinez-Hernandez F, et al. Parasitol Res. 2020 Jan;119(1):97-104. doi: 10.1007/s00436-019-06530-4. Epub 2019 Nov 17. Parasitol Res. 2020. PMID: 31735993
In addition, a large variety of animals have been reported as hosts of the parasite, and new hosts and STs are still being described. In this study, Blastocystis infection of wild animals in two sylvatic areas of Mexico was surveyed. Of one hundred twenty-four fecal sample …
In addition, a large variety of animals have been reported as hosts of the parasite, and new hosts and STs are still being described. In thi …
237 results