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Exploring the enigmatic association between PNLIP variants and risk of chronic pancreatitis in a large Chinese cohort.
Pancreatology. 2024 Mar 7:S1424-3903(24)00064-4. doi: 10.1016/j.pan.2024.03.002. Online ahead of print.
Pancreatology. 2024.
PMID: 38485544
Characterization of novel PNLIP variants in congenital pancreatic lipase deficiency.
Lin J, Matiwala N, Curry GE, Wilhelm SJ, Cassidy BM, Lowe ME, Xiao X.
Lin J, et al. Among authors: wilhelm sj.
Pancreatology. 2023 Dec;23(8):1036-1040. doi: 10.1016/j.pan.2023.10.022. Epub 2023 Oct 31.
Pancreatology. 2023.
PMID: 37926600
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The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice.
Fjeld K, Gravdal A, Brekke RS, Alam J, Wilhelm SJ, El Jellas K, Pettersen HN, Lin J, Solheim MH, Steine SJ, Johansson BB, Njølstad PR, Verbeke CS, Xiao X, Lowe ME, Molven A.
Fjeld K, et al. Among authors: wilhelm sj.
Pancreatology. 2022 Dec;22(8):1099-1111. doi: 10.1016/j.pan.2022.11.003. Epub 2022 Nov 9.
Pancreatology. 2022.
PMID: 36379850
Free article.
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Preclinical mouse model of a misfolded PNLIP variant develops chronic pancreatitis.
Zhu G, Wilhelm SJ, George LG, Cassidy BM, Zino S, Luke CJ, Hanna M, Stone S, Phan N, Matiwala N, Ballentine SJ, Lowe ME, Xiao X.
Zhu G, et al. Among authors: wilhelm sj.
Gut. 2023 Jul;72(7):1340-1354. doi: 10.1136/gutjnl-2022-327960. Epub 2023 Jan 11.
Gut. 2023.
PMID: 36631248
Free PMC article.
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Common single-base insertions in the VNTR of the carboxyl ester lipase (CEL) gene are benign and also likely to arise somatically in the exocrine pancreas.
Brekke RS, Gravdal A, El Jellas K, Curry GE, Lin J, Wilhelm SJ, Steine SJ, Mas E, Johansson S, Lowe ME, Johansson BB, Xiao X, Fjeld K, Molven A.
Brekke RS, et al. Among authors: wilhelm sj.
Hum Mol Genet. 2024 Mar 14:ddae034. doi: 10.1093/hmg/ddae034. Online ahead of print.
Hum Mol Genet. 2024.
PMID: 38483348
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