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In Vitro Activation of Cytochrome P450 46A1 (CYP46A1) by Efavirenz-Related Compounds.
J Med Chem. 2020 Jun 25;63(12):6477-6488. doi: 10.1021/acs.jmedchem.9b01383. Epub 2019 Nov 3.
J Med Chem. 2020.
PMID: 31617715
Free PMC article.
Conformational selection dominates binding of steroids to human cytochrome P450 17A1.
Guengerich FP, Wilkey CJ, Glass SM, Reddish MJ.
Guengerich FP, et al. Among authors: wilkey cj.
J Biol Chem. 2019 Jun 28;294(26):10028-10041. doi: 10.1074/jbc.RA119.008860. Epub 2019 May 9.
J Biol Chem. 2019.
PMID: 31072872
Free PMC article.
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Human cytochrome P450 enzymes bind drugs and other substrates mainly through conformational-selection modes.
Guengerich FP, Wilkey CJ, Phan TTN.
Guengerich FP, et al. Among authors: wilkey cj.
J Biol Chem. 2019 Jul 12;294(28):10928-10941. doi: 10.1074/jbc.RA119.009305. Epub 2019 May 30.
J Biol Chem. 2019.
PMID: 31147443
Free PMC article.
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Glutamine-451 Confers Sensitivity to Oxidative Inhibition and Heme-Thiolate Sulfenylation of Cytochrome P450 4B1.
Albertolle ME, Song HD, Wilkey CJ, Segrest JP, Guengerich FP.
Albertolle ME, et al. Among authors: wilkey cj.
Chem Res Toxicol. 2019 Mar 18;32(3):484-492. doi: 10.1021/acs.chemrestox.8b00353. Epub 2019 Feb 11.
Chem Res Toxicol. 2019.
PMID: 30701961
Free PMC article.
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Characterization of human adrenal cytochrome P450 11B2 products of progesterone and androstenedione oxidation.
Glass SM, Reddish MJ, Child SA, Wilkey CJ, Stec DF, Guengerich FP.
Glass SM, et al. Among authors: wilkey cj.
J Steroid Biochem Mol Biol. 2021 Apr;208:105787. doi: 10.1016/j.jsbmb.2020.105787. Epub 2020 Nov 12.
J Steroid Biochem Mol Biol. 2021.
PMID: 33189850
Free PMC article.
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Correction: Human cytochrome P450 enzymes bind drugs and other substrates mainly through conformational-selection modes.
Guengerich FP, Wilkey CJ, Phan TTN.
Guengerich FP, et al. Among authors: wilkey cj.
J Biol Chem. 2019 Oct 25;294(43):15875. doi: 10.1074/jbc.AAC119.011301.
J Biol Chem. 2019.
PMID: 31653773
Free PMC article.
No abstract available.
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Correction to Glutamine-451 Confers Sensitivity to Oxidative Inhibition and Heme-Thiolate Sulfenylation of Cytochrome P450 4B1.
Albertolle ME, Song HD, Wilkey CJ, Segrest JP, Guengerich FP.
Albertolle ME, et al. Among authors: wilkey cj.
Chem Res Toxicol. 2021 Mar 15;34(3):930. doi: 10.1021/acs.chemrestox.0c00538. Epub 2021 Jan 21.
Chem Res Toxicol. 2021.
PMID: 33475339
No abstract available.
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