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Strain and near attack conformers in enzymic thiamin catalysis: X-ray crystallographic snapshots of bacterial transketolase in covalent complex with donor ketoses xylulose 5-phosphate and fructose 6-phosphate, and in noncovalent complex with acceptor aldose ribose 5-phosphate.
Asztalos P, Parthier C, Golbik R, Kleinschmidt M, Hübner G, Weiss MS, Friedemann R, Wille G, Tittmann K. Asztalos P, et al. Among authors: wille g. Biochemistry. 2007 Oct 30;46(43):12037-52. doi: 10.1021/bi700844m. Epub 2007 Oct 3. Biochemistry. 2007. PMID: 17914867
Radical phosphate transfer mechanism for the thiamin diphosphate- and FAD-dependent pyruvate oxidase from Lactobacillus plantarum. Kinetic coupling of intercofactor electron transfer with phosphate transfer to acetyl-thiamin diphosphate via a transient FAD semiquinone/hydroxyethyl-ThDP radical pair.
Tittmann K, Wille G, Golbik R, Weidner A, Ghisla S, Hübner G. Tittmann K, et al. Among authors: wille g. Biochemistry. 2005 Oct 11;44(40):13291-303. doi: 10.1021/bi051058z. Biochemistry. 2005. PMID: 16201755
Caged CO(2) for the direct observation of CO(2)-consuming reactions.
Lommel K, Schäfer G, Grenader K, Ruland C, Terfort A, Mäntele W, Wille G. Lommel K, et al. Among authors: wille g. Chembiochem. 2013 Feb 11;14(3):372-80. doi: 10.1002/cbic.201200659. Epub 2013 Jan 16. Chembiochem. 2013. PMID: 23325631
85 results