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Epistasis, core-genome disharmony, and adaptation in recombining bacteria.
Taylor AJ, Yahara K, Pascoe B, Ko S, Mageiros L, Mourkas E, Calland JK, Puranen S, Hitchings MD, Jolley KA, Kobras CM, Bayliss S, Williams NJ, van Vliet AHM, Parkhill J, Maiden MCJ, Corander J, Hurst LD, Falush D, Keim P, Didelot X, Kelly DJ, Sheppard SK. Taylor AJ, et al. Among authors: williams nj. mBio. 2024 Apr 29:e0058124. doi: 10.1128/mbio.00581-24. Online ahead of print. mBio. 2024. PMID: 38683013 Free article.
Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia.
Rosenthal ZC, Fass DM, Payne NC, She A, Patnaik D, Hennig KM, Tesla R, Werthmann GC, Guhl C, Reis SA, Wang X, Chen Y, Placzek M, Williams NS, Hooker J, Herz J, Mazitschek R, Haggarty SJ. Rosenthal ZC, et al. Among authors: williams ns. Sci Rep. 2024 Apr 20;14(1):9064. doi: 10.1038/s41598-024-59110-7. Sci Rep. 2024. PMID: 38643236 Free PMC article.
Safety of a controlled human infection model of tuberculosis with aerosolised, live-attenuated Mycobacterium bovis BCG versus intradermal BCG in BCG-naive adults in the UK: a dose-escalation, randomised, controlled, phase 1 trial.
Satti I, Marshall JL, Harris SA, Wittenberg R, Tanner R, Lopez Ramon R, Wilkie M, Ramos Lopez F, Riste M, Wright D, Peralta Alvarez MP, Williams N, Morrison H, Stylianou E, Folegatti P, Jenkin D, Vermaak S, Rask L, Cabrera Puig I, Powell Doherty R, Lawrie A, Moss P, Hinks T, Bettinson H, McShane H. Satti I, et al. Among authors: williams n. Lancet Infect Dis. 2024 Apr 12:S1473-3099(24)00143-9. doi: 10.1016/S1473-3099(24)00143-9. Online ahead of print. Lancet Infect Dis. 2024. PMID: 38621405 Free article.
4,713 results