Wilson CG - Search Results

1

Small-Molecule Screening for Genetic Diseases.

Markossian S, Ang KK, Wilson CG, Arkin MR. Markossian S, et al. Among authors: wilson cg. Annu Rev Genomics Hum Genet. 2018 Aug 31;19:263-288. doi: 10.1146/annurev-genom-083117-021452. Epub 2018 May 23. Annu Rev Genomics Hum Genet. 2018. PMID: 29799800 Review.

2

Small-molecule inhibitors of IL-2/IL-2R: lessons learned and applied.

Wilson CG, Arkin MR. Wilson CG, et al. Curr Top Microbiol Immunol. 2011;348:25-59. doi: 10.1007/82_2010_93. Curr Top Microbiol Immunol. 2011. PMID: 20703966

3

Pharmacological brake-release of mRNA translation enhances cognitive memory.

Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn BR, Li H, Gamache K, Gallagher CM, Ang KK, Wilson C, Okreglak V, Ashkenazi A, Hann B, Nader K, Arkin MR, Renslo AR, Sonenberg N, Walter P. Sidrauski C, et al. Elife. 2013 May 28;2:e00498. doi: 10.7554/eLife.00498. Elife. 2013. PMID: 23741617 Free PMC article.

4

Probing structural adaptivity at PPI interfaces with small molecules.

Wilson CG, Arkin MR. Wilson CG, et al. Drug Discov Today Technol. 2013 Dec;10(4):e501-8. doi: 10.1016/j.ddtec.2012.10.009. Drug Discov Today Technol. 2013. PMID: 24451641 Review.

5

UCSF Small Molecule Discovery Center: innovation, collaboration and chemical biology in the Bay Area.

Arkin MR, Ang KK, Chen S, Davies J, Merron C, Tang Y, Wilson CG, Renslo AR. Arkin MR, et al. Among authors: wilson cg. Comb Chem High Throughput Screen. 2014 May;17(4):333-42. doi: 10.2174/1386207317666140323133841. Comb Chem High Throughput Screen. 2014. PMID: 24661212

6

Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding.

Visperas PR, Winger JA, Horton TM, Shah NH, Aum DJ, Tao A, Barros T, Yan Q, Wilson CG, Arkin MR, Weiss A, Kuriyan J. Visperas PR, et al. Among authors: wilson cg. Biochem J. 2015 Jan 1;465(1):149-61. doi: 10.1042/BJ20140793. Biochem J. 2015. PMID: 25287889 Free PMC article.

7

Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis.

Bulman CA, Bidlow CM, Lustigman S, Cho-Ngwa F, Williams D, Rascón AA Jr, Tricoche N, Samje M, Bell A, Suzuki B, Lim KC, Supakorndej N, Supakorndej P, Wolfe AR, Knudsen GM, Chen S, Wilson C, Ang KH, Arkin M, Gut J, Franklin C, Marcellino C, McKerrow JH, Debnath A, Sakanari JA. Bulman CA, et al. PLoS Negl Trop Dis. 2015 Feb 20;9(2):e0003534. doi: 10.1371/journal.pntd.0003534. eCollection 2015 Feb. PLoS Negl Trop Dis. 2015. PMID: 25700363 Free PMC article.

8

A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver.

Suzawa M, Miranda DA, Ramos KA, Ang KK, Faivre EJ, Wilson CG, Caboni L, Arkin MR, Kim YS, Fletterick RJ, Diaz A, Schneekloth JS, Ingraham HA. Suzawa M, et al. Among authors: wilson cg. Elife. 2015 Dec 11;4:e09003. doi: 10.7554/eLife.09003. Elife. 2015. PMID: 26653140 Free PMC article.

9

Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch.

Gallagher CM, Garri C, Cain EL, Ang KK, Wilson CG, Chen S, Hearn BR, Jaishankar P, Aranda-Diaz A, Arkin MR, Renslo AR, Walter P. Gallagher CM, et al. Among authors: wilson cg. Elife. 2016 Jul 20;5:e11878. doi: 10.7554/eLife.11878. Elife. 2016. PMID: 27435960 Free PMC article.

10

Identification of Inhibitors of the Association of ZAP-70 with the T Cell Receptor by High-Throughput Screen.

Visperas PR, Wilson CG, Winger JA, Yan Q, Lin K, Arkin MR, Weiss A, Kuriyan J. Visperas PR, et al. Among authors: wilson cg. SLAS Discov. 2017 Mar;22(3):324-331. doi: 10.1177/1087057116681407. Epub 2016 Dec 13. SLAS Discov. 2017. PMID: 27932698 Free PMC article.

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