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The Three Rs - do we need a new principle?
Wittevrongel C. Wittevrongel C. Altern Lab Anim. 2013 Nov;41(5):P56-7. doi: 10.1177/026119291304100510. Altern Lab Anim. 2013. PMID: 24329747 No abstract available.
Unravelling the disease mechanism for TSPYL1 deficiency.
Buyse G, Di Michele M, Wijgaerts A, Louwette S, Wittevrongel C, Thys C, Downes K, Ceulemans B, Van Esch H, Van Geet C, Freson K. Buyse G, et al. Among authors: wittevrongel c. Hum Mol Genet. 2020 Dec 18;29(20):3431-3442. doi: 10.1093/hmg/ddaa233. Hum Mol Genet. 2020. PMID: 33075815
Methylome analysis for spina bifida shows SOX18 hypomethylation as a risk factor with evidence for a complex (epi)genetic interplay to affect neural tube development.
Rochtus A, Winand R, Laenen G, Vangeel E, Izzi B, Wittevrongel C, Moreau Y, Verpoorten C, Jansen K, Van Geet C, Freson K. Rochtus A, et al. Among authors: wittevrongel c. Clin Epigenetics. 2016 Oct 13;8:108. doi: 10.1186/s13148-016-0272-8. eCollection 2016. Clin Epigenetics. 2016. PMID: 27757173 Free PMC article.
A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies.
Turro E, Greene D, Wijgaerts A, Thys C, Lentaigne C, Bariana TK, Westbury SK, Kelly AM, Selleslag D, Stephens JC, Papadia S, Simeoni I, Penkett CJ, Ashford S, Attwood A, Austin S, Bakchoul T, Collins P, Deevi SV, Favier R, Kostadima M, Lambert MP, Mathias M, Millar CM, Peerlinck K, Perry DJ, Schulman S, Whitehorn D, Wittevrongel C; BRIDGE-BPD Consortium; De Maeyer M, Rendon A, Gomez K, Erber WN, Mumford AD, Nurden P, Stirrups K, Bradley JR, Raymond FL, Laffan MA, Van Geet C, Richardson S, Freson K, Ouwehand WH. Turro E, et al. Among authors: wittevrongel c. Sci Transl Med. 2016 Mar 2;8(328):328ra30. doi: 10.1126/scitranslmed.aad7666. Epub 2016 Mar 2. Sci Transl Med. 2016. PMID: 26936507 Free PMC article.
Methylation defect in imprinted genes detected in patients with an Albright's hereditary osteodystrophy like phenotype and platelet Gs hypofunction.
Izzi B, Francois I, Labarque V, Thys C, Wittevrongel C, Devriendt K, Legius E, Van den Bruel A, D'Hooghe M, Lambrechts D, de Zegher F, Van Geet C, Freson K. Izzi B, et al. Among authors: wittevrongel c. PLoS One. 2012;7(6):e38579. doi: 10.1371/journal.pone.0038579. Epub 2012 Jun 5. PLoS One. 2012. PMID: 22679513 Free PMC article.
40 results