Wolter M - Search Results

1

An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-κB-Utilizing a Reversible Covalent Tethering Approach.

Wolter M, Valenti D, Cossar PJ, Hristeva S, Levy LM, Genski T, Hoffmann T, Brunsveld L, Tzalis D, Ottmann C. Wolter M, et al. J Med Chem. 2021 Jun 24;64(12):8423-8436. doi: 10.1021/acs.jmedchem.1c00401. Epub 2021 Jun 2. J Med Chem. 2021. PMID: 34076416 Free PMC article.

2

Structural characterization of 14-3-3ζ in complex with the human Son of sevenless homolog 1 (SOS1).

Ballone A, Centorrino F, Wolter M, Ottmann C. Ballone A, et al. Among authors: wolter m. J Struct Biol. 2018 Jun;202(3):210-215. doi: 10.1016/j.jsb.2018.01.011. Epub 2018 Feb 1. J Struct Biol. 2018. PMID: 29408703

3

Biophysical and structural insight into the USP8/14-3-3 interaction.

Centorrino F, Ballone A, Wolter M, Ottmann C. Centorrino F, et al. Among authors: wolter m. FEBS Lett. 2018 Apr;592(7):1211-1220. doi: 10.1002/1873-3468.13017. Epub 2018 Mar 2. FEBS Lett. 2018. PMID: 29473952 Free article.

4

Protein X-ray crystallography of the 14-3-3ζ/SOS1 complex.

Ballone A, Centorrino F, Wolter M, Ottmann C. Ballone A, et al. Among authors: wolter m. Data Brief. 2018 Jun 28;19:1683-1687. doi: 10.1016/j.dib.2018.06.060. eCollection 2018 Aug. Data Brief. 2018. PMID: 30229043 Free PMC article.

5

AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins.

Saline M, Badertscher L, Wolter M, Lau R, Gunnarsson A, Jacso T, Norris T, Ottmann C, Snijder A. Saline M, et al. Among authors: wolter m. J Biol Chem. 2019 Aug 30;294(35):13106-13116. doi: 10.1074/jbc.RA119.008649. Epub 2019 Jul 15. J Biol Chem. 2019. PMID: 31308176 Free PMC article.

6

Interaction of an IκBα Peptide with 14-3-3.

Wolter M, Santo DL, Herman P, Ballone A, Centorrino F, Obsil T, Ottmann C. Wolter M, et al. ACS Omega. 2020 Mar 6;5(10):5380-5388. doi: 10.1021/acsomega.9b04413. eCollection 2020 Mar 17. ACS Omega. 2020. PMID: 32201828 Free PMC article.

7

Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 Interaction with Semisynthetic Natural Products.

Wolter M, de Vink P, Neves JF, Srdanović S, Higuchi Y, Kato N, Wilson A, Landrieu I, Brunsveld L, Ottmann C. Wolter M, et al. J Am Chem Soc. 2020 Jul 8;142(27):11772-11783. doi: 10.1021/jacs.0c02151. Epub 2020 Jun 23. J Am Chem Soc. 2020. PMID: 32501683 Free PMC article.

8

Fragment-based Differential Targeting of PPI Stabilizer Interfaces.

Guillory X, Wolter M, Leysen S, Neves JF, Kuusk A, Genet S, Somsen B, Morrow JK, Rivers E, van Beek L, Patel J, Goodnow R, Schoenherr H, Fuller N, Cao Q, Doveston RG, Brunsveld L, Arkin MR, Castaldi P, Boyd H, Landrieu I, Chen H, Ottmann C. Guillory X, et al. Among authors: wolter m. J Med Chem. 2020 Jul 9;63(13):6694-6707. doi: 10.1021/acs.jmedchem.9b01942. Epub 2020 Jun 23. J Med Chem. 2020. PMID: 32501690 Free PMC article.

9

Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based Tethering.

Wolter M, Valenti D, Cossar PJ, Levy LM, Hristeva S, Genski T, Hoffmann T, Brunsveld L, Tzalis D, Ottmann C. Wolter M, et al. Angew Chem Int Ed Engl. 2020 Nov 23;59(48):21520-21524. doi: 10.1002/anie.202008585. Epub 2020 Sep 25. Angew Chem Int Ed Engl. 2020. PMID: 32816380 Free PMC article.

10

Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions.

Cossar PJ, Wolter M, van Dijck L, Valenti D, Levy LM, Ottmann C, Brunsveld L. Cossar PJ, et al. Among authors: wolter m. J Am Chem Soc. 2021 Jun 9;143(22):8454-8464. doi: 10.1021/jacs.1c03035. Epub 2021 May 28. J Am Chem Soc. 2021. PMID: 34047554 Free PMC article.

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