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Encephalitis patient-derived monoclonal GABAA receptor antibodies cause epileptic seizures.
Kreye J, Wright SK, van Casteren A, Stöffler L, Machule ML, Reincke SM, Nikolaus M, van Hoof S, Sanchez-Sendin E, Homeyer MA, Cordero Gómez C, Kornau HC, Schmitz D, Kaindl AM, Boehm-Sturm P, Mueller S, Wilson MA, Upadhya MA, Dhangar DR, Greenhill S, Woodhall G, Turko P, Vida I, Garner CC, Wickel J, Geis C, Fukata Y, Fukata M, Prüss H. Kreye J, et al. Among authors: woodhall g. J Exp Med. 2021 Nov 1;218(11):e20210012. doi: 10.1084/jem.20210012. Epub 2021 Sep 21. J Exp Med. 2021. PMID: 34546336 Free PMC article.
Multimodal electrophysiological analyses reveal that reduced synaptic excitatory neurotransmission underlies seizures in a model of NMDAR antibody-mediated encephalitis.
Wright SK, Rosch RE, Wilson MA, Upadhya MA, Dhangar DR, Clarke-Bland C, Wahid TT, Barman S, Goebels N, Kreye J, Prüss H, Jacobson L, Bassett DS, Vincent A, Greenhill SD, Woodhall GL. Wright SK, et al. Among authors: woodhall gl. Commun Biol. 2021 Sep 20;4(1):1106. doi: 10.1038/s42003-021-02635-8. Commun Biol. 2021. PMID: 34545200 Free PMC article.
The AMPA receptor antagonist perampanel suppresses epileptic activity in human focal cortical dysplasia.
Brito da Silva A, Pennifold J, Henley B, Chatterjee K, Bateman D, Whittaker RW, Joshi A, Kumar H, Nicholson C, Baker MR, Greenhill SD, Walsh R, Seri S, Jones RSG, Woodhall GL, Cunningham MO. Brito da Silva A, et al. Among authors: woodhall gl. Epilepsia Open. 2022 Sep;7(3):488-495. doi: 10.1002/epi4.12549. Epub 2022 May 11. Epilepsia Open. 2022. PMID: 34653311 Free PMC article.
51 results