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The long and short of it: the influence of N-carboxyethyl versusN-carboxymethyl pendant arms on in vitro and in vivo behavior of copper complexes of cross-bridged tetraamine macrocycles.
Heroux KJ, Woodin KS, Tranchemontagne DJ, Widger PC, Southwick E, Wong EH, Weisman GR, Tomellini SA, Wadas TJ, Anderson CJ, Kassel S, Golen JA, Rheingold AL. Heroux KJ, et al. Among authors: woodin ks. Dalton Trans. 2007 Jun 7;(21):2150-62. doi: 10.1039/b702938a. Epub 2007 Apr 16. Dalton Trans. 2007. PMID: 17514336 Free PMC article.
Synthesis and activity of substituted carbamates as potentiators of the alpha4beta2 nicotinic acetylcholine receptor.
Springer SK, Woodin KS, Berry V, Boezio AA, Cao L, Clarkin K, Harmange JC, Hierl M, Knop J, Malmberg AB, McDermott JS, Nguyen HQ, Waldon D, Albrecht BK, McDonough SI. Springer SK, et al. Among authors: woodin ks. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5643-7. doi: 10.1016/j.bmcl.2008.08.092. Epub 2008 Aug 29. Bioorg Med Chem Lett. 2008. PMID: 18805006
Discovery and optimization of substituted piperidines as potent, selective, CNS-penetrant alpha4beta2 nicotinic acetylcholine receptor potentiators.
Albrecht BK, Berry V, Boezio AA, Cao L, Clarkin K, Guo W, Harmange JC, Hierl M, Huang L, Janosky B, Knop J, Malmberg A, McDermott JS, Nguyen HQ, Springer SK, Waldon D, Woodin K, McDonough SI. Albrecht BK, et al. Bioorg Med Chem Lett. 2008 Oct 1;18(19):5209-12. doi: 10.1016/j.bmcl.2008.08.080. Epub 2008 Aug 28. Bioorg Med Chem Lett. 2008. PMID: 18789861