Woychik NA - Search Results

1

An RNA-seq method for defining endoribonuclease cleavage specificity identifies dual rRNA substrates for toxin MazF-mt3.

Schifano JM, Vvedenskaya IO, Knoblauch JG, Ouyang M, Nickels BE, Woychik NA. Schifano JM, et al. Among authors: woychik na. Nat Commun. 2014 Apr 8;5:3538. doi: 10.1038/ncomms4538. Nat Commun. 2014. PMID: 24709835 Free PMC article.

2

Bacterial toxin YafQ is an endoribonuclease that associates with the ribosome and blocks translation elongation through sequence-specific and frame-dependent mRNA cleavage.

Prysak MH, Mozdzierz CJ, Cook AM, Zhu L, Zhang Y, Inouye M, Woychik NA. Prysak MH, et al. Among authors: woychik na. Mol Microbiol. 2009 Mar;71(5):1071-87. doi: 10.1111/j.1365-2958.2008.06572.x. Epub 2009 Jan 30. Mol Microbiol. 2009. PMID: 19210620 Free article.

3

Bacterial toxin HigB associates with ribosomes and mediates translation-dependent mRNA cleavage at A-rich sites.

Hurley JM, Woychik NA. Hurley JM, et al. Among authors: woychik na. J Biol Chem. 2009 Jul 10;284(28):18605-13. doi: 10.1074/jbc.M109.008763. Epub 2009 May 7. J Biol Chem. 2009. PMID: 19423702 Free PMC article.

4

Noncognate Mycobacterium tuberculosis toxin-antitoxins can physically and functionally interact.

Zhu L, Sharp JD, Kobayashi H, Woychik NA, Inouye M. Zhu L, et al. Among authors: woychik na. J Biol Chem. 2010 Dec 17;285(51):39732-8. doi: 10.1074/jbc.M110.163105. Epub 2010 Sep 27. J Biol Chem. 2010. PMID: 20876537 Free PMC article.

5

Bacterial toxin RelE mediates frequent codon-independent mRNA cleavage from the 5' end of coding regions in vivo.

Hurley JM, Cruz JW, Ouyang M, Woychik NA. Hurley JM, et al. Among authors: woychik na. J Biol Chem. 2011 Apr 29;286(17):14770-8. doi: 10.1074/jbc.M110.108969. Epub 2011 Feb 15. J Biol Chem. 2011. PMID: 21324908 Free PMC article.

6

Growth and translation inhibition through sequence-specific RNA binding by Mycobacterium tuberculosis VapC toxin.

Sharp JD, Cruz JW, Raman S, Inouye M, Husson RN, Woychik NA. Sharp JD, et al. Among authors: woychik na. J Biol Chem. 2012 Apr 13;287(16):12835-47. doi: 10.1074/jbc.M112.340109. Epub 2012 Feb 21. J Biol Chem. 2012. PMID: 22354968 Free PMC article.

7

Clostridium difficile MazF toxin exhibits selective, not global, mRNA cleavage.

Rothenbacher FP, Suzuki M, Hurley JM, Montville TJ, Kirn TJ, Ouyang M, Woychik NA. Rothenbacher FP, et al. Among authors: woychik na. J Bacteriol. 2012 Jul;194(13):3464-74. doi: 10.1128/JB.00217-12. Epub 2012 Apr 27. J Bacteriol. 2012. PMID: 22544268 Free PMC article.

8

Mycobacterial toxin MazF-mt6 inhibits translation through cleavage of 23S rRNA at the ribosomal A site.

Schifano JM, Edifor R, Sharp JD, Ouyang M, Konkimalla A, Husson RN, Woychik NA. Schifano JM, et al. Among authors: woychik na. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8501-6. doi: 10.1073/pnas.1222031110. Epub 2013 May 6. Proc Natl Acad Sci U S A. 2013. PMID: 23650345 Free PMC article.

9

Doc toxin is a kinase that inactivates elongation factor Tu.

Cruz JW, Rothenbacher FP, Maehigashi T, Lane WS, Dunham CM, Woychik NA. Cruz JW, et al. Among authors: woychik na. J Biol Chem. 2014 Mar 14;289(11):7788-98. doi: 10.1074/jbc.M113.544429. Epub 2014 Jan 21. J Biol Chem. 2014. PMID: 24448800 Free PMC article.

10

23S rRNA as an a-Maz-ing new bacterial toxin target.

Schifano JM, Woychik NA. Schifano JM, et al. Among authors: woychik na. RNA Biol. 2014;11(2):101-5. doi: 10.4161/rna.27949. Epub 2014 Feb 7. RNA Biol. 2014. PMID: 24525465 Free PMC article.

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