Wrennall JA - Search Results

1

Understanding how cystic fibrosis mutations disrupt CFTR function: from single molecules to animal models.

Wang Y, Wrennall JA, Cai Z, Li H, Sheppard DN. Wang Y, et al. Among authors: wrennall ja. Int J Biochem Cell Biol. 2014 Jul;52:47-57. doi: 10.1016/j.biocel.2014.04.001. Epub 2014 Apr 13. Int J Biochem Cell Biol. 2014. PMID: 24727426 Review.

2

Two Small Molecules Restore Stability to a Subpopulation of the Cystic Fibrosis Transmembrane Conductance Regulator with the Predominant Disease-causing Mutation.

Meng X, Wang Y, Wang X, Wrennall JA, Rimington TL, Li H, Cai Z, Ford RC, Sheppard DN. Meng X, et al. Among authors: wrennall ja. J Biol Chem. 2017 Mar 3;292(9):3706-3719. doi: 10.1074/jbc.M116.751537. Epub 2017 Jan 13. J Biol Chem. 2017. PMID: 28087700 Free PMC article.

3

A SPLUNC1 Peptidomimetic Inhibits Orai1 and Reduces Inflammation in a Murine Allergic Asthma Model.

Wrennall JA, Ahmad S, Worthington EN, Wu T, Goriounova AS, Voeller AS, Stewart IE, Ghosh A, Krajewski K, Tilley SL, Hickey AJ, Sassano MF, Tarran R. Wrennall JA, et al. Am J Respir Cell Mol Biol. 2022 Mar;66(3):271-282. doi: 10.1165/rcmb.2020-0452OC. Am J Respir Cell Mol Biol. 2022. PMID: 34807800 Free PMC article.

4

Super resolution microscopy analysis reveals increased Orai1 activity in asthma and cystic fibrosis lungs.

Goriounova AS, Gilmore RC, Wrennall JA, Tarran R. Goriounova AS, et al. Among authors: wrennall ja. J Cyst Fibros. 2023 Jan;22(1):161-171. doi: 10.1016/j.jcf.2022.07.003. Epub 2022 Aug 10. J Cyst Fibros. 2023. PMID: 35961837 Free PMC article.

5

Passaging Primary Human Bronchial Epithelia Reduces CFTR-Mediated Fluid Transport and Alters mRNA Expression.

Wu T, Wrennall JA, Dang H, Baines DL, Tarran R. Wu T, et al. Among authors: wrennall ja. Cells. 2023 Mar 24;12(7):997. doi: 10.3390/cells12070997. Cells. 2023. PMID: 37048070 Free PMC article.

6

Chronic E-Cigarette Exposure Alters Human Alveolar Macrophage Morphology and Gene Expression.

Davis ES, Ghosh A, Coakley RD, Wrennall JA, Lubamba BA, Rowell TR, Dang H, Pawlak EA, Li Q, Alexis NE, Ribeiro CMP, Tarran R. Davis ES, et al. Among authors: wrennall ja. Nicotine Tob Res. 2022 Feb 14;24(3):395-399. doi: 10.1093/ntr/ntab186. Nicotine Tob Res. 2022. PMID: 34519792 Free PMC article.

7

Combustible and Electronic Cigarette Exposures Increase ACE2 Activity and SARS-CoV-2 Spike Binding.

Ghosh A, Girish V, Yuan ML, Coakley RD, Wrennall JA, Alexis NE, Sausville EL, Vasudevan A, Chait AR, Sheltzer JM, Tarran R. Ghosh A, et al. Among authors: wrennall ja. Am J Respir Crit Care Med. 2022 Jan 1;205(1):129-133. doi: 10.1164/rccm.202106-1377LE. Am J Respir Crit Care Med. 2022. PMID: 34748720 Free PMC article. No abstract available.

8

[No title available]

[No authors listed] [No authors listed] PMID: 35556998

9

SPLUNC1 is a negative regulator of the Orai1 Ca²⁺ channel.

Wu T, Goriounova AS, Worthington EN, Wrennall JA, Ghosh A, Ahmad S, Flori Sassano M, Tarran R. Wu T, et al. Among authors: wrennall ja. Physiol Rep. 2022 May;10(10):e15306. doi: 10.14814/phy2.15306. Physiol Rep. 2022. PMID: 35581745 Free PMC article.

10

Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an Acute Respiratory Distress Syndrome Model.

Ahmad S, Wrennall JA, Goriounova AS, Sekhri M, Iskarpatyoti JA, Ghosh A, Abdelwahab SH, Voeller A, Rai M, Mahida RY, Krajewski K, Ignar DM, Greenbaum A, Moran TP, Tilley SL, Thickett DR, Sassano MF, Tarran R. Ahmad S, et al. Among authors: wrennall ja. Am J Respir Crit Care Med. 2024 Mar 15;209(6):703-715. doi: 10.1164/rccm.202308-1393OC. Am J Respir Crit Care Med. 2024. PMID: 37972349

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