Wright MC - Search Results

1

Pregnenolone-16alpha-carbonitrile inhibits rodent liver fibrogenesis via PXR (pregnane X receptor)-dependent and PXR-independent mechanisms.

Marek CJ, Tucker SJ, Konstantinou DK, Elrick LJ, Haefner D, Sigalas C, Murray GI, Goodwin B, Wright MC. Marek CJ, et al. Among authors: wright mc. Biochem J. 2005 May 1;387(Pt 3):601-8. doi: 10.1042/BJ20041598. Biochem J. 2005. PMID: 15595924 Free PMC article.

2

Generation of hepatocytes expressing functional cytochromes P450 from a pancreatic progenitor cell line in vitro.

Marek CJ, Cameron GA, Elrick LJ, Hawksworth GM, Wright MC. Marek CJ, et al. Among authors: wright mc. Biochem J. 2003 Mar 15;370(Pt 3):763-9. doi: 10.1042/BJ20021545. Biochem J. 2003. PMID: 12542397 Free PMC article.

3

Pregnane X receptor activators inhibit human hepatic stellate cell transdifferentiation in vitro.

Haughton EL, Tucker SJ, Marek CJ, Durward E, Leel V, Bascal Z, Monaghan T, Koruth M, Collie-Duguid E, Mann DA, Trim JE, Wright MC. Haughton EL, et al. Among authors: wright mc. Gastroenterology. 2006 Jul;131(1):194-209. doi: 10.1053/j.gastro.2006.04.012. Gastroenterology. 2006. PMID: 16831602

4

Identification of a truncated ratp28-related protein expressed in kidney.

Leel V, Elrick LJ, Solares J, Ingram N, Charlton KA, Porter AJ, Wright MC. Leel V, et al. Among authors: wright mc. Biochem Biophys Res Commun. 2004 Apr 9;316(3):872-7. doi: 10.1016/j.bbrc.2004.02.137. Biochem Biophys Res Commun. 2004. PMID: 15033482

5

Mechanism of action of the antifibrogenic compound gliotoxin in rat liver cells.

Orr JG, Leel V, Cameron GA, Marek CJ, Haughton EL, Elrick LJ, Trim JE, Hawksworth GM, Halestrap AP, Wright MC. Orr JG, et al. Among authors: wright mc. Hepatology. 2004 Jul;40(1):232-42. doi: 10.1002/hep.20254. Hepatology. 2004. PMID: 15239107

6

Generation of a monoclonal human single chain antibody fragment to hepatic stellate cells--a potential mechanism for targeting liver anti-fibrotic therapeutics.

Elrick LJ, Leel V, Blaylock MG, Duncan L, Drever MR, Strachan G, Charlton KA, Koruth M, Porter AJ, Wright MC. Elrick LJ, et al. Among authors: wright mc. J Hepatol. 2005 Jun;42(6):888-96. doi: 10.1016/j.jhep.2005.01.028. Epub 2005 Apr 8. J Hepatol. 2005. PMID: 15885360

7

Expression of CYP2S1 in human hepatic stellate cells.

Marek CJ, Tucker SJ, Koruth M, Wallace K, Wright MC. Marek CJ, et al. Among authors: wright mc. FEBS Lett. 2007 Feb 20;581(4):781-6. doi: 10.1016/j.febslet.2007.01.056. Epub 2007 Feb 2. FEBS Lett. 2007. PMID: 17280660 Free article.

8

The PXR is a drug target for chronic inflammatory liver disease.

Wallace K, Cowie DE, Konstantinou DK, Hill SJ, Tjelle TE, Axon A, Koruth M, White SA, Carlsen H, Mann DA, Wright MC. Wallace K, et al. Among authors: wright mc. J Steroid Biochem Mol Biol. 2010 May 31;120(2-3):137-48. doi: 10.1016/j.jsbmb.2010.04.012. Epub 2010 Apr 21. J Steroid Biochem Mol Biol. 2010. PMID: 20416375 Free PMC article.

9

Low affinity glucocorticoid binding site ligands as potential anti-fibrogenics.

Marek CJ, Wallace K, Durward E, Koruth M, Leel V, Leiper LJ, Wright MC. Marek CJ, et al. Among authors: wright mc. Comp Hepatol. 2009 May 11;8:1. doi: 10.1186/1476-5926-8-1. Comp Hepatol. 2009. PMID: 19432992 Free PMC article.

10

Exocrine pancreas trans-differentiation to hepatocytes--a physiological response to elevated glucocorticoid in vivo.

Wallace K, Marek CJ, Currie RA, Wright MC. Wallace K, et al. Among authors: wright mc. J Steroid Biochem Mol Biol. 2009 Aug;116(1-2):76-85. doi: 10.1016/j.jsbmb.2009.05.002. Epub 2009 May 13. J Steroid Biochem Mol Biol. 2009. PMID: 19446026

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