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Pharmacokinetics and metabolism of the prodrug DB289 (2,5-bis[4-(N-methoxyamidino)phenyl]furan monomaleate) in rat and monkey and its conversion to the antiprotozoal/antifungal drug DB75 (2,5-bis(4-guanylphenyl)furan dihydrochloride).
Midgley I, Fitzpatrick K, Taylor LM, Houchen TL, Henderson SJ, Wright SJ, Cybulski ZR, John BA, McBurney A, Boykin DW, Trendler KL. Midgley I, et al. Among authors: wright sj. Drug Metab Dispos. 2007 Jun;35(6):955-67. doi: 10.1124/dmd.106.013391. Epub 2007 Mar 14. Drug Metab Dispos. 2007. PMID: 17360833
Toward a coordinated understanding of hydro-biogeochemical root functions in tropical forests for application in vegetation models.
Cusack DF, Christoffersen B, Smith-Martin CM, Andersen KM, Cordeiro AL, Fleischer K, Wright SJ, Guerrero-Ramírez NR, Lugli LF, McCulloch LA, Sanchez-Julia M, Batterman SA, Dallstream C, Fortunel C, Toro L, Fuchslueger L, Wong MY, Yaffar D, Fisher JB, Arnaud M, Dietterich LH, Addo-Danso SD, Valverde-Barrantes OJ, Weemstra M, Ng JC, Norby RJ. Cusack DF, et al. Among authors: wright sj. New Phytol. 2024 Apr;242(2):351-371. doi: 10.1111/nph.19561. Epub 2024 Feb 28. New Phytol. 2024. PMID: 38416367 Free article.
Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy.
Revach OY, Cicerchia AM, Shorer O, Petrova B, Anderson S, Park J, Chen L, Mehta A, Wright SJ, McNamee N, Tal-Mason A, Cattaneo G, Tiwari P, Xie H, Sweere JM, Cheng LC, Sigal N, Enrico E, Miljkovic M, Evans SA, Nguyen N, Whidden ME, Srinivasan R, Spitzer MH, Sun Y, Sharova T, Lawless AR, Michaud WA, Rasmussen MQ, Fang J, Palin CA, Chen F, Wang X, Ferrone CR, Lawrence DP, Sullivan RJ, Liu D, Sachdeva UM, Sen DR, Flaherty KT, Manguso RT, Bod L, Kellis M, Boland GM, Yizhak K, Yang J, Kanarek N, Sade-Feldman M, Hacohen N, Jenkins RW. Revach OY, et al. Among authors: wright sj. bioRxiv [Preprint]. 2024 Mar 26:2024.02.12.579184. doi: 10.1101/2024.02.12.579184. bioRxiv. 2024. PMID: 38405985 Free PMC article. Preprint.
Early Immune Remodeling Steers Clinical Response to First-Line Chemoimmunotherapy in Advanced Gastric Cancer.
An M, Mehta A, Min BH, Heo YJ, Wright SJ, Parikh M, Bi L, Lee H, Kim TJ, Lee SY, Moon J, Park RJ, Strickland MR, Park WY, Kang WK, Kim KM, Kim ST, Klempner SJ, Lee J. An M, et al. Among authors: wright sj. Cancer Discov. 2024 May 1;14(5):766-785. doi: 10.1158/2159-8290.CD-23-0857. Cancer Discov. 2024. PMID: 38319303 Free PMC article. Clinical Trial.
296 results