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Discovery of a novel shp2 protein tyrosine phosphatase inhibitor.
Chen L, Sung SS, Yip ML, Lawrence HR, Ren Y, Guida WC, Sebti SM, Lawrence NJ, Wu J. Chen L, et al. Among authors: wu j. Mol Pharmacol. 2006 Aug;70(2):562-70. doi: 10.1124/mol.106.025536. Epub 2006 May 22. Mol Pharmacol. 2006. PMID: 16717135
Enhanced anti-melanoma efficacy of interferon alfa-2b via inhibition of Shp2.
Win-Piazza H, Schneeberger VE, Chen L, Pernazza D, Lawrence HR, Sebti SM, Lawrence NJ, Wu J. Win-Piazza H, et al. Among authors: wu j. Cancer Lett. 2012 Jul 1;320(1):81-5. doi: 10.1016/j.canlet.2012.01.034. Epub 2012 Feb 1. Cancer Lett. 2012. PMID: 22306001 Free PMC article.
Inhibition of cellular Shp2 activity by a methyl ester analog of SPI-112.
Chen L, Pernazza D, Scott LM, Lawrence HR, Ren Y, Luo Y, Wu X, Sung SS, Guida WC, Sebti SM, Lawrence NJ, Wu J. Chen L, et al. Among authors: wu x, wu j. Biochem Pharmacol. 2010 Sep 15;80(6):801-10. doi: 10.1016/j.bcp.2010.05.019. Epub 2010 May 25. Biochem Pharmacol. 2010. PMID: 20510203 Free PMC article.
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