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14 results
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Candidate tumor suppressor DDX3 RNA helicase specifically represses cap-dependent translation by acting as an eIF4E inhibitory protein.
Shih JW, Tsai TY, Chao CH, Wu Lee YH. Shih JW, et al. Among authors: wu lee yh. Oncogene. 2008 Jan 24;27(5):700-14. doi: 10.1038/sj.onc.1210687. Epub 2007 Jul 30. Oncogene. 2008. PMID: 17667941
YB-1 disrupts mismatch repair complex formation, interferes with MutSĪ± recruitment on mismatch and inhibits mismatch repair through interacting with PCNA.
Chang YW, Mai RT, Fang WH, Lin CC, Chiu CC, Wu Lee YH. Chang YW, et al. Among authors: wu lee yh. Oncogene. 2014 Oct 23;33(43):5065-77. doi: 10.1038/onc.2013.450. Epub 2013 Oct 21. Oncogene. 2014. PMID: 24141788
Hepatitis C virus core protein recruits nucleolar phosphoprotein B23 and coactivator p300 to relieve the repression effect of transcriptional factor YY1 on B23 gene expression.
Mai RT, Yeh TS, Kao CF, Sun SK, Huang HH, Wu Lee YH. Mai RT, et al. Among authors: wu lee yh. Oncogene. 2006 Jan 19;25(3):448-62. doi: 10.1038/sj.onc.1209052. Oncogene. 2006. PMID: 16170350
DDX3, a DEAD box RNA helicase, is deregulated in hepatitis virus-associated hepatocellular carcinoma and is involved in cell growth control.
Chang PC, Chi CW, Chau GY, Li FY, Tsai YH, Wu JC, Wu Lee YH. Chang PC, et al. Among authors: wu lee yh. Oncogene. 2006 Mar 30;25(14):1991-2003. doi: 10.1038/sj.onc.1209239. Oncogene. 2006. PMID: 16301996
Membrane protein-regulated networks across human cancers.
Lin CY, Lee CH, Chuang YH, Lee JY, Chiu YY, Wu Lee YH, Jong YJ, Hwang JK, Huang SH, Chen LC, Wu CH, Tu SH, Ho YS, Yang JM. Lin CY, et al. Among authors: wu lee yh. Nat Commun. 2019 Jul 16;10(1):3131. doi: 10.1038/s41467-019-10920-8. Nat Commun. 2019. PMID: 31311925 Free PMC article.
RNA helicase DDX3 maintains lipid homeostasis through upregulation of the microsomal triglyceride transfer protein by interacting with HNF4 and SHP.
Tsai TY, Wang WT, Li HK, Chen WJ, Tsai YH, Chao CH, Wu Lee YH. Tsai TY, et al. Among authors: wu lee yh. Sci Rep. 2017 Jan 27;7:41452. doi: 10.1038/srep41452. Sci Rep. 2017. PMID: 28128295 Free PMC article.
Targeted inactivation of murine Ddx3x: essential roles of Ddx3x in placentation and embryogenesis.
Chen CY, Chan CH, Chen CM, Tsai YS, Tsai TY, Wu Lee YH, You LR. Chen CY, et al. Among authors: wu lee yh. Hum Mol Genet. 2016 Jul 15;25(14):2905-2922. doi: 10.1093/hmg/ddw143. Epub 2016 May 14. Hum Mol Genet. 2016. PMID: 27179789
Y-Box Binding Protein 1 Stabilizes Hepatitis C Virus NS5A via Phosphorylation-Mediated Interaction with NS5A To Regulate Viral Propagation.
Wang WT, Tsai TY, Chao CH, Lai BY, Wu Lee YH. Wang WT, et al. Among authors: wu lee yh. J Virol. 2015 Nov;89(22):11584-602. doi: 10.1128/JVI.01513-15. Epub 2015 Sep 9. J Virol. 2015. PMID: 26355086 Free PMC article.
Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response.
Shih JW, Wang WT, Tsai TY, Kuo CY, Li HK, Wu Lee YH. Shih JW, et al. Among authors: wu lee yh. Biochem J. 2012 Jan 1;441(1):119-29. doi: 10.1042/BJ20110739. Biochem J. 2012. PMID: 21883093
The CBF1-independent Notch1 signal pathway activates human c-myc expression partially via transcription factor YY1.
Liao WR, Hsieh RH, Hsu KW, Wu MZ, Tseng MJ, Mai RT, Wu Lee YH, Yeh TS. Liao WR, et al. Among authors: wu lee yh. Carcinogenesis. 2007 Sep;28(9):1867-76. doi: 10.1093/carcin/bgm092. Epub 2007 Apr 13. Carcinogenesis. 2007. PMID: 17434929
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