A multistage Sendai virus vaccine incorporating latency-associated antigens induces protection against acute and latent tuberculosis.
Hu Z, Xia J, Wu J, Zhao H, Ji P, Gu L, Gu W, Chen Z, Xu J, Huang X, Ma J, Chen A, Li J, Shu T, Fan XY.
Hu Z, et al.
Emerg Microbes Infect. 2024 Dec;13(1):2300463. doi: 10.1080/22221751.2023.2300463. Epub 2024 Jan 4.
Emerg Microbes Infect. 2024.
PMID: 38164736
Free PMC article.
Enhanced immune protection against the Mtb challenge was shown in both acute-infection and latent-infection murine models. The expression levels of several T-cell exhaustion markers were significantly lower in the SeV986A-vaccinated group, suggesting that the expression of …
Enhanced immune protection against the Mtb challenge was shown in both acute-infection and latent-infection murine models. The expression le …