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Genetic inhibition of Na+-Ca2+ exchanger current disables fight or flight sinoatrial node activity without affecting resting heart rate.
Gao Z, Rasmussen TP, Li Y, Kutschke W, Koval OM, Wu Y, Wu Y, Hall DD, Joiner ML, Wu XQ, Swaminathan PD, Purohit A, Zimmerman K, Weiss RM, Philipson KD, Song LS, Hund TJ, Anderson ME. Gao Z, et al. Among authors: wu y, wu xq. Circ Res. 2013 Jan 18;112(2):309-17. doi: 10.1161/CIRCRESAHA.111.300193. Epub 2012 Nov 27. Circ Res. 2013. PMID: 23192947 Free PMC article.
Two-Pore K+ Channel TREK-1 Regulates Sinoatrial Node Membrane Excitability.
Unudurthi SD, Wu X, Qian L, Amari F, Onal B, Li N, Makara MA, Smith SA, Snyder J, Fedorov VV, Coppola V, Anderson ME, Mohler PJ, Hund TJ. Unudurthi SD, et al. J Am Heart Assoc. 2016 Apr 20;5(4):e002865. doi: 10.1161/JAHA.115.002865. J Am Heart Assoc. 2016. PMID: 27098968 Free PMC article.
β(IV)-Spectrin regulates TREK-1 membrane targeting in the heart.
Hund TJ, Snyder JS, Wu X, Glynn P, Koval OM, Onal B, Leymaster ND, Unudurthi SD, Curran J, Camardo C, Wright PJ, Binkley PF, Anderson ME, Mohler PJ. Hund TJ, et al. Cardiovasc Res. 2014 Apr 1;102(1):166-75. doi: 10.1093/cvr/cvu008. Epub 2014 Jan 20. Cardiovasc Res. 2014. PMID: 24445605 Free PMC article.
Protein phosphatase 2A regulatory subunit B56α limits phosphatase activity in the heart.
Little SC, Curran J, Makara MA, Kline CF, Ho HT, Xu Z, Wu X, Polina I, Musa H, Meadows AM, Carnes CA, Biesiadecki BJ, Davis JP, Weisleder N, Györke S, Wehrens XH, Hund TJ, Mohler PJ. Little SC, et al. Sci Signal. 2015 Jul 21;8(386):ra72. doi: 10.1126/scisignal.aaa5876. Sci Signal. 2015. PMID: 26198358 Free PMC article.
499 results