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Calmodulin kinase II inhibition protects against structural heart disease.
Zhang R, Khoo MS, Wu Y, Yang Y, Grueter CE, Ni G, Price EE Jr, Thiel W, Guatimosim S, Song LS, Madu EC, Shah AN, Vishnivetskaya TA, Atkinson JB, Gurevich VV, Salama G, Lederer WJ, Colbran RJ, Anderson ME. Zhang R, et al. Among authors: wu y. Nat Med. 2005 Apr;11(4):409-17. doi: 10.1038/nm1215. Epub 2005 Mar 27. Nat Med. 2005. PMID: 15793582
Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy.
Khoo MS, Li J, Singh MV, Yang Y, Kannankeril P, Wu Y, Grueter CE, Guan X, Oddis CV, Zhang R, Mendes L, Ni G, Madu EC, Yang J, Bass M, Gomez RJ, Wadzinski BE, Olson EN, Colbran RJ, Anderson ME. Khoo MS, et al. Among authors: wu y. Circulation. 2006 Sep 26;114(13):1352-9. doi: 10.1161/CIRCULATIONAHA.106.644583. Epub 2006 Sep 18. Circulation. 2006. PMID: 16982937
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