Wu Y - Search Results

1

The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction.

Wu Y, Zhou X, Barnes CO, DeLucia M, Cohen AE, Gronenborn AM, Ahn J, Calero G. Wu Y, et al. Nat Struct Mol Biol. 2016 Oct;23(10):933-940. doi: 10.1038/nsmb.3284. Epub 2016 Aug 29. Nat Struct Mol Biol. 2016. PMID: 27571178 Free PMC article.

2

Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A.

Byeon IL, Calero G, Wu Y, Byeon CH, Jung J, DeLucia M, Zhou X, Weiss S, Ahn J, Hao C, Skowronski J, Gronenborn AM. Byeon IL, et al. Among authors: wu y. Nat Commun. 2021 Nov 25;12(1):6864. doi: 10.1038/s41467-021-27009-w. Nat Commun. 2021. PMID: 34824204 Free PMC article.

3

HIV-2 and SIVmac accessory virulence factor Vpx down-regulates SAMHD1 enzyme catalysis prior to proteasome-dependent degradation.

DeLucia M, Mehrens J, Wu Y, Ahn J. DeLucia M, et al. Among authors: wu y. J Biol Chem. 2013 Jun 28;288(26):19116-26. doi: 10.1074/jbc.M113.469007. Epub 2013 May 15. J Biol Chem. 2013. PMID: 23677995 Free PMC article.

4

Mechanism of allosteric activation of SAMHD1 by dGTP.

Ji X, Wu Y, Yan J, Mehrens J, Yang H, DeLucia M, Hao C, Gronenborn AM, Skowronski J, Ahn J, Xiong Y. Ji X, et al. Among authors: wu y. Nat Struct Mol Biol. 2013 Nov;20(11):1304-9. doi: 10.1038/nsmb.2692. Epub 2013 Oct 20. Nat Struct Mol Biol. 2013. PMID: 24141705 Free PMC article.

5

Structural basis of allosteric activation of sterile α motif and histidine-aspartate domain-containing protein 1 (SAMHD1) by nucleoside triphosphates.

Koharudin LM, Wu Y, DeLucia M, Mehrens J, Gronenborn AM, Ahn J. Koharudin LM, et al. Among authors: wu y. J Biol Chem. 2014 Nov 21;289(47):32617-27. doi: 10.1074/jbc.M114.591958. Epub 2014 Oct 6. J Biol Chem. 2014. PMID: 25288794 Free PMC article.

6

Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile α Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.

Wu Y, Koharudin LMI, Mehrens J, DeLucia M, Byeon CH, Byeon IL, Calero G, Ahn J, Gronenborn AM. Wu Y, et al. J Biol Chem. 2015 Jul 17;290(29):17935-17945. doi: 10.1074/jbc.M115.665513. Epub 2015 Jun 4. J Biol Chem. 2015. PMID: 26045556 Free PMC article.

7

Transmission electron microscopy for the evaluation and optimization of crystal growth.

Stevenson HP, Lin G, Barnes CO, Sutkeviciute I, Krzysiak T, Weiss SC, Reynolds S, Wu Y, Nagarajan V, Makhov AM, Lawrence R, Lamm E, Clark L, Gardella TJ, Hogue BG, Ogata CM, Ahn J, Gronenborn AM, Conway JF, Vilardaga JP, Cohen AE, Calero G. Stevenson HP, et al. Among authors: wu y. Acta Crystallogr D Struct Biol. 2016 May;72(Pt 5):603-15. doi: 10.1107/S2059798316001546. Epub 2016 Apr 26. Acta Crystallogr D Struct Biol. 2016. PMID: 27139624 Free PMC article.

8

The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.

Barnes CO, Wu Y, Song J, Lin G, Baxter EL, Brewster AS, Nagarajan V, Holmes A, Soltis SM, Sauter NK, Ahn J, Cohen AE, Calero G. Barnes CO, et al. Among authors: wu y. Proc Natl Acad Sci U S A. 2019 May 7;116(19):9333-9339. doi: 10.1073/pnas.1814999116. Epub 2019 Apr 24. Proc Natl Acad Sci U S A. 2019. PMID: 31019074 Free PMC article.

9

Mechanisms of allosteric activation and inhibition of the deoxyribonucleoside triphosphate triphosphohydrolase from Enterococcus faecalis.

Vorontsov II, Wu Y, DeLucia M, Minasov G, Mehrens J, Shuvalova L, Anderson WF, Ahn J. Vorontsov II, et al. Among authors: wu y. J Biol Chem. 2014 Jan 31;289(5):2815-24. doi: 10.1074/jbc.M113.524207. Epub 2013 Dec 12. J Biol Chem. 2014. PMID: 24338016 Free PMC article.

10

SAMHD1 Gene Mutations Are Associated with Cerebral Large-Artery Atherosclerosis.

Li W, Xin B, Yan J, Wu Y, Hu B, Liu L, Wang Y, Ahn J, Skowronski J, Zhang Z, Wang Y, Wang H. Li W, et al. Among authors: wu y. Biomed Res Int. 2015;2015:739586. doi: 10.1155/2015/739586. Epub 2015 Oct 4. Biomed Res Int. 2015. PMID: 26504826 Free PMC article.

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