Wu YZ - Search Results

1

Wu-5, a novel USP10 inhibitor, enhances crenolanib-induced FLT3-ITD-positive AML cell death via inhibiting FLT3 and AMPK pathways.

Yu M, Fang ZX, Wang WW, Zhang Y, Bu ZL, Liu M, Xiao XH, Zhang ZL, Zhang XM, Cao Y, Wang YY, Lei H, Xu HZ, Wu YZ, Liu W, Wu YL. Yu M, et al. Among authors: wu yz, wu yl. Acta Pharmacol Sin. 2021 Apr;42(4):604-612. doi: 10.1038/s41401-020-0455-x. Epub 2020 Jul 21. Acta Pharmacol Sin. 2021. PMID: 32694757 Free PMC article.

2

Characterization of naturally occurring pentacyclic triterpenes as novel inhibitors of deubiquitinating protease USP7 with anticancer activity in vitro.

Jing B, Liu M, Yang L, Cai HY, Chen JB, Li ZX, Kou X, Wu YZ, Qin DJ, Zhou L, Jin J, Lei H, Xu HZ, Wang WW, Wu YL. Jing B, et al. Among authors: wu yz, wu yl. Acta Pharmacol Sin. 2018 Mar;39(3):492-498. doi: 10.1038/aps.2017.119. Epub 2017 Nov 23. Acta Pharmacol Sin. 2018. PMID: 29168472 Free PMC article.

3

Targeting USP47 overcomes tyrosine kinase inhibitor resistance and eradicates leukemia stem/progenitor cells in chronic myelogenous leukemia.

Lei H, Xu HZ, Shan HZ, Liu M, Lu Y, Fang ZX, Jin J, Jing B, Xiao XH, Gao SM, Gao FH, Xia L, Yang L, Liu LG, Wang WW, Liu CX, Tong Y, Wu YZ, Zheng JK, Chen GQ, Zhou L, Wu YL. Lei H, et al. Among authors: wu yz, wu yl. Nat Commun. 2021 Jan 4;12(1):51. doi: 10.1038/s41467-020-20259-0. Nat Commun. 2021. PMID: 33397955 Free PMC article.

4

CDDO-Me reveals USP7 as a novel target in ovarian cancer cells.

Qin D, Wang W, Lei H, Luo H, Cai H, Tang C, Wu Y, Wang Y, Jin J, Xiao W, Wang T, Ma C, Xu H, Zhang J, Gao F, Wu YL. Qin D, et al. Oncotarget. 2016 Nov 22;7(47):77096-77109. doi: 10.18632/oncotarget.12801. Oncotarget. 2016. PMID: 27780924 Free PMC article.

5

YL064 activates proteasomal-dependent degradation of c-Myc and synergistically enhances the anti-tumor activity of ABT-199 in diffuse large B cell lymphoma.

Shan H, Cao Y, Xiao X, Liu M, Wu Y, Zhu Q, Xu H, Lei H, Yao Z, Wu Y. Shan H, et al. Signal Transduct Target Ther. 2020 Jul 6;5(1):116. doi: 10.1038/s41392-020-00236-1. Signal Transduct Target Ther. 2020. PMID: 32632092 Free PMC article. No abstract available.

6

Hsp90/C terminal Hsc70-interacting protein regulates the stability of Ikaros in acute myeloid leukemia cells.

Liu M, Jin J, Ji Y, Shan H, Zou Z, Cao Y, Yang L, Liu L, Zhou L, Lei H, Wu Y, Xu H, Wu Y. Liu M, et al. Sci China Life Sci. 2021 Sep;64(9):1481-1490. doi: 10.1007/s11427-020-1860-2. Epub 2021 Jan 8. Sci China Life Sci. 2021. PMID: 33439458

7

ZCL-082, a boron-containing compound, induces apoptosis of non-Hodgkin's lymphoma via targeting p90 ribosomal S6 kinase 1/NF-κB signaling pathway.

Ma C, Liu M, Zhang J, Cai H, Wu Y, Zhang Y, Ji Y, Shan H, Zou Z, Yang L, Liu L, Xu H, Lei H, Liu C, Zhou L, Cao Y, Zhou H, Wu Y. Ma C, et al. Chem Biol Interact. 2022 Jan 5;351:109770. doi: 10.1016/j.cbi.2021.109770. Epub 2021 Nov 30. Chem Biol Interact. 2022. PMID: 34861246

8

IKZF1 selectively enhances homologous recombination repair by interacting with CtIP and USP7 in multiple myeloma.

Liu M, Zhang Y, Wu Y, Jin J, Cao Y, Fang Z, Geng L, Yang L, Yu M, Bu Z, Ji Y, Shan H, Zou Z, Liu L, Wang Y, Zhang Y, Tong Y, Xu H, Lei H, Liu W, Gao F, Wu Y. Liu M, et al. Int J Biol Sci. 2022 Mar 21;18(6):2515-2526. doi: 10.7150/ijbs.70960. eCollection 2022. Int J Biol Sci. 2022. PMID: 35414773 Free PMC article.

9

Parthenolide reveals an allosteric mode to inhibit the deISGylation activity of SARS-CoV‑2 papain-like protease.

Zou Z, Shan H, Sun D, Xia L, Shi Y, Wan J, Zhou A, Wu Y, Xu H, Lei H, Xu Z, Wu Y. Zou Z, et al. Acta Biochim Biophys Sin (Shanghai). 2022 Aug 25;54(8):1133-1139. doi: 10.3724/abbs.2022092. Acta Biochim Biophys Sin (Shanghai). 2022. PMID: 35866602 Free PMC article.

10

A novel "mosaic-type" nanoparticle for selective drug release targeting hypoxic cancer cells.

Wang W , Li X , Wang Z , Zhang J , Dong X , Wu Y , Fang C , Zhou A , Wu Y . Wang W , et al. Nanoscale. 2019 Jan 31;11(5):2211-2222. doi: 10.1039/c8nr06452k. Nanoscale. 2019. PMID: 30656317

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