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Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis.
Köhler R, Wulff H, Eichler I, Kneifel M, Neumann D, Knorr A, Grgic I, Kämpfe D, Si H, Wibawa J, Real R, Borner K, Brakemeier S, Orzechowski HD, Reusch HP, Paul M, Chandy KG, Hoyer J. Köhler R, et al. Among authors: wulff h. Circulation. 2003 Sep 2;108(9):1119-25. doi: 10.1161/01.CIR.0000086464.04719.DD. Epub 2003 Aug 25. Circulation. 2003. PMID: 12939222 Free article.
K+ channels as targets for specific immunomodulation.
Chandy KG, Wulff H, Beeton C, Pennington M, Gutman GA, Cahalan MD. Chandy KG, et al. Among authors: wulff h. Trends Pharmacol Sci. 2004 May;25(5):280-9. doi: 10.1016/j.tips.2004.03.010. Trends Pharmacol Sci. 2004. PMID: 15120495 Free PMC article. Review.
Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a new activator of KCa2 and KCa3.1 potassium channels, potentiates the endothelium-derived hyperpolarizing factor response and lowers blood pressure.
Sankaranarayanan A, Raman G, Busch C, Schultz T, Zimin PI, Hoyer J, Köhler R, Wulff H. Sankaranarayanan A, et al. Among authors: wulff h. Mol Pharmacol. 2009 Feb;75(2):281-95. doi: 10.1124/mol.108.051425. Epub 2008 Oct 27. Mol Pharmacol. 2009. PMID: 18955585 Free PMC article.
Genetic deficit of SK3 and IK1 channels disrupts the endothelium-derived hyperpolarizing factor vasodilator pathway and causes hypertension.
Brähler S, Kaistha A, Schmidt VJ, Wölfle SE, Busch C, Kaistha BP, Kacik M, Hasenau AL, Grgic I, Si H, Bond CT, Adelman JP, Wulff H, de Wit C, Hoyer J, Köhler R. Brähler S, et al. Among authors: wulff h. Circulation. 2009 May 5;119(17):2323-32. doi: 10.1161/CIRCULATIONAHA.108.846634. Epub 2009 Apr 20. Circulation. 2009. PMID: 19380617 Free article.
Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels.
Grgic I, Kiss E, Kaistha BP, Busch C, Kloss M, Sautter J, Müller A, Kaistha A, Schmidt C, Raman G, Wulff H, Strutz F, Gröne HJ, Köhler R, Hoyer J. Grgic I, et al. Among authors: wulff h. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14518-23. doi: 10.1073/pnas.0903458106. Epub 2009 Aug 13. Proc Natl Acad Sci U S A. 2009. PMID: 19706538 Free PMC article.
497 results