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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1979 1
1981 3
1982 3
1983 5
1984 2
1985 5
1986 4
1987 5
1988 6
1989 9
1990 11
1991 7
1992 18
1993 12
1994 12
1995 25
1996 22
1997 21
1998 20
1999 26
2000 41
2001 41
2002 26
2003 31
2004 28
2005 39
2006 43
2007 39
2008 36
2009 38
2010 52
2011 46
2012 39
2013 34
2014 33
2015 45
2016 52
2017 40
2018 38
2019 23
2020 33
2021 24
2022 22
2023 13
2024 8

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985 results

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Page 1
Downregulated XPA promotes carcinogenesis of bladder cancer via impairment of DNA repair.
Zhi Y, Ji H, Pan J, He P, Zhou X, Zhang H, Zhou Z, Chen Z. Zhi Y, et al. Tumour Biol. 2017 Feb;39(2):1010428317691679. doi: 10.1177/1010428317691679. Tumour Biol. 2017. PMID: 28222669 Free article.
However, participation of XPA in the repair of DNA double-strand break remains unknown. Here, we reported that bladder cancer expressed low XPA levels compared to adjacent non-tumor bladder tissue, and this phenotype was closely associated with chromosomal ab …
However, participation of XPA in the repair of DNA double-strand break remains unknown. Here, we reported that bladder cancer …
Xpa knockout mice.
de Vries A, van Steeg H. de Vries A, et al. Semin Cancer Biol. 1996 Oct;7(5):229-40. doi: 10.1006/scbi.1996.0031. Semin Cancer Biol. 1996. PMID: 9110400 Review.
As such the XPA protein participates in the initial step of the process of nucleotide excision repair. ...Furthermore, the possible use of Xpa- and other nucleotide excision repair deficient mice in cancer research will be outlined in more detail....
As such the XPA protein participates in the initial step of the process of nucleotide excision repair. ...Furthermore, the possible u …
Genetic variation of XPA gene and risk of cancer: a systematic review and pooled analysis.
Ding D, Zhang Y, Yu H, Guo Y, Jiang L, He X, Ma W, Zheng W. Ding D, et al. Int J Cancer. 2012 Jul 15;131(2):488-96. doi: 10.1002/ijc.26391. Epub 2011 Oct 20. Int J Cancer. 2012. PMID: 21866550 Free article. Review.
XPA, a zinc-finger DNA-binding protein, play an important role in both global genome and transcription-coupled repair pathways. ...When stratified by ethnicity, significantly elevated risks were observed among Asian populations (AA versus GG: OR = 1.31, 95% CI = 1.01-1.70; …
XPA, a zinc-finger DNA-binding protein, play an important role in both global genome and transcription-coupled repair pathways. ...Wh …
Association of XPA polymorphism with breast cancer risk: A meta-analysis.
Zhang Y, Guo Q, Yin X, Zhu X, Zhao L, Zhang Z, Wei R, Wang B, Li X. Zhang Y, et al. Medicine (Baltimore). 2018 Jun;97(26):e11276. doi: 10.1097/MD.0000000000011276. Medicine (Baltimore). 2018. PMID: 29953005 Free PMC article.
CONCLUSION: XPA rs1800975 polymorphism may decrease the risk of breast cancer in both non-Asians and population-based patients. Large sample size and well-designed study is needed for further assessing the role of XPA polymorphism in breast cancer risk …
CONCLUSION: XPA rs1800975 polymorphism may decrease the risk of breast cancer in both non-Asians and population-based patients …
DNA repair protein XPA is differentially expressed in colorectal cancer and predicts better prognosis.
Feng X, Liu J, Gong Y, Gou K, Yang H, Yuan Y, Xing C. Feng X, et al. Cancer Med. 2018 Jun;7(6):2339-2349. doi: 10.1002/cam4.1480. Epub 2018 Apr 19. Cancer Med. 2018. PMID: 29675892 Free PMC article.
The expression characteristics of XPA in colorectal cancer (CRC) and its influence on CRC prognosis remain elusive. ...DNA repair protein XPA is significantly decreased in colorectal cancer tissues than in adjacent nontumor tissues. ...
The expression characteristics of XPA in colorectal cancer (CRC) and its influence on CRC prognosis remain elusive. ...DNA rep …
Cadmium and cancer.
Hartwig A. Hartwig A. Met Ions Life Sci. 2013;11:491-507. doi: 10.1007/978-94-007-5179-8_15. Met Ions Life Sci. 2013. PMID: 23430782 Free article. Review.
Cadmium is an established human and animal carcinogen. Most evidence is available for elevated risk for lung cancer after occupational exposure; however, associations between cadmium exposure and tumors at other locations including kidney, breast, and prostate may be relev …
Cadmium is an established human and animal carcinogen. Most evidence is available for elevated risk for lung cancer after occupationa …
XPA: DNA Repair Protein of Significant Clinical Importance.
Borszéková Pulzová L, Ward TA, Chovanec M. Borszéková Pulzová L, et al. Int J Mol Sci. 2020 Mar 22;21(6):2182. doi: 10.3390/ijms21062182. Int J Mol Sci. 2020. PMID: 32235701 Free PMC article. Review.
XPA functions in damage verification step in NER, as well as a molecular scaffold to assemble other NER core factors around the DNA damage site, mediated by protein-protein interactions. In this review, we focus on the interacting partners and mechanisms of regulation of t …
XPA functions in damage verification step in NER, as well as a molecular scaffold to assemble other NER core factors around the DNA d …
Association of XPA Polymorphisms Towards Lung Cancer Susceptibility and its Predictive Role in Overall Survival of North Indians.
Lawania S, Singh N, Behera D, Sharma S. Lawania S, et al. Biochem Genet. 2018 Aug;56(4):375-396. doi: 10.1007/s10528-018-9850-0. Epub 2018 Mar 7. Biochem Genet. 2018. PMID: 29516319
The present study investigated the role of Xeroderma pigmentosum group A (XPA) polymorphism (A23G and G709A) with lung cancer risk and its association with overall survival in North Indians. 370 cases and 370 controls were investigated to evaluate association betwee …
The present study investigated the role of Xeroderma pigmentosum group A (XPA) polymorphism (A23G and G709A) with lung cancer …
Association between XPA gene rs1800975 polymorphism and susceptibility to lung cancer: a meta-analysis.
Liu X, Lin Q, Fu C, Liu C, Zhu F, Liu Z, Li S, Jiang L. Liu X, et al. Clin Respir J. 2018 Feb;12(2):448-458. doi: 10.1111/crj.12535. Epub 2016 Aug 21. Clin Respir J. 2018. PMID: 27460688
It was reported that XPA rs1800975 polymorphism was associated with susceptibility to lung cancer. ...AA, AG + GG vs. AA). CONCLUSIONS: This meta-analysis suggested that the XPA gene rs1800975 Polymorphism was associated with lung cancer susceptibility …
It was reported that XPA rs1800975 polymorphism was associated with susceptibility to lung cancer. ...AA, AG + GG vs. AA). CON …
XPA A23G polymorphism and susceptibility to cancer: a meta-analysis.
Liu J, Zhang Z, Cao XL, Lei DP, Wang ZQ, Jin T, Pan XL. Liu J, et al. Mol Biol Rep. 2012 Jun;39(6):6791-9. doi: 10.1007/s11033-012-1504-4. Mol Biol Rep. 2012. PMID: 22314912
Overall, no significant association of XPA A23G variant with cancer susceptibility was observed for any genetic model. ...The meta-analysis suggested that the XPA A23G G allele is a low-penetrant risk factor for cancer development....
Overall, no significant association of XPA A23G variant with cancer susceptibility was observed for any genetic model. ...The …
985 results