Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2019 2
2020 23
2021 3
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

23 results

Results by year

Filters applied: . Clear all
Page 1
PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis.
Hou J, Zhao R, Xia W, Chang CW, You Y, Hsu JM, Nie L, Chen Y, Wang YC, Liu C, Wang WJ, Wu Y, Ke B, Hsu JL, Huang K, Ye Z, Yang Y, Xia X, Li Y, Li CW, Shao B, Tainer JA, Hung MC. Hou J, et al. Nat Cell Biol. 2020 Oct;22(10):1264-1275. doi: 10.1038/s41556-020-0575-z. Epub 2020 Sep 14. Nat Cell Biol. 2020. PMID: 32929201 Free PMC article.
GSDMC is specifically cleaved by caspase-8 with TNFalpha treatment, generating a GSDMC N-terminal domain that forms pores on the cell membrane and induces pyroptosis. Nuclear PD-L1, caspase-8 and GSDMC are required for macrophage-derived TNFalpha-induced tumour necrosis in …
GSDMC is specifically cleaved by caspase-8 with TNFalpha treatment, generating a GSDMC N-terminal domain that forms pores on the cell …
Ferroptosis Is Involved in Diabetes Myocardial Ischemia/Reperfusion Injury Through Endoplasmic Reticulum Stress.
Li W, Li W, Leng Y, Xiong Y, Xia Z. Li W, et al. DNA Cell Biol. 2020 Feb;39(2):210-225. doi: 10.1089/dna.2019.5097. Epub 2019 Dec 6. DNA Cell Biol. 2020. PMID: 31809190
In DM+sham (DS) (or HG) and I/R (or H/R) models, cardiomyocytes were injured accompanied by increased level of ferroptosis and ERS. Moreover, the cell injury was more serious in rat DIR or cell HH/R models. Inhibition of ferroptosis in DIR model could reduce ERS and …
In DM+sham (DS) (or HG) and I/R (or H/R) models, cardiomyocytes were injured accompanied by increased level of ferroptosis and ERS. Moreover …
Interaction Between microRNA and DNA Methylation in Atherosclerosis.
Tao J, Xia L, Cai Z, Liang L, Chen Y, Meng J, Wang Z. Tao J, et al. DNA Cell Biol. 2021 Jan;40(1):101-115. doi: 10.1089/dna.2020.6138. Epub 2020 Dec 1. DNA Cell Biol. 2021. PMID: 33259723 Review.
Atherosclerosis (AS) is a chronic inflammatory disease accompanied by complex pathological changes, such as endothelial dysfunction, foam cell formation, and vascular smooth muscle cell proliferation. Many approaches, including regulating AS-related gene expression …
Atherosclerosis (AS) is a chronic inflammatory disease accompanied by complex pathological changes, such as endothelial dysfunction, foam …
Transcription Factor RREB1: from Target Genes towards Biological Functions.
Deng YN, Xia Z, Zhang P, Ejaz S, Liang S. Deng YN, et al. Int J Biol Sci. 2020 Feb 21;16(8):1463-1473. doi: 10.7150/ijbs.40834. eCollection 2020. Int J Biol Sci. 2020. PMID: 32210733 Free PMC article. Review.
The Ras-responsive element binding protein 1(RREB1) is a member of zinc finger transcription factors, which is widely involved in biological processes including cell proliferation, transcriptional regulation and DNA damage repair. ...
The Ras-responsive element binding protein 1(RREB1) is a member of zinc finger transcription factors, which is widely involved in biological …
Potential roles of telomeres and telomerase in neurodegenerative diseases.
Wang J, Liu Y, Xia Q, Xia Q, Wang B, Yang C, Liang J, Liu X. Wang J, et al. Int J Biol Macromol. 2020 Nov 15;163:1060-1078. doi: 10.1016/j.ijbiomac.2020.07.046. Epub 2020 Jul 13. Int J Biol Macromol. 2020. PMID: 32673712 Review.
Telomeres, protective DNA-protein complexes at the end of eukaryotic linear chromosomes, play pivotal roles in the maintenance of genomic stability during cell division. ...
Telomeres, protective DNA-protein complexes at the end of eukaryotic linear chromosomes, play pivotal roles in the maintenance of gen …
microRNA-196a Overexpression Inhibits Apoptosis in Hemin-Induced K562 Cells.
Zhao X, Liu Z, Shen J, Yong L, Xia Y, Bian M. Zhao X, et al. DNA Cell Biol. 2020 Feb;39(2):235-243. doi: 10.1089/dna.2019.5061. Epub 2020 Jan 8. DNA Cell Biol. 2020. PMID: 31913716
However, the understanding of the apoptosis of erythroid lineage remains poorly understood. Hence, an additional examination is required. K562 cell lines can be differentiated into early erythrocytes by hemin and the model of early erythrocytes can be established, conseque …
However, the understanding of the apoptosis of erythroid lineage remains poorly understood. Hence, an additional examination is required. K5 …
MiR-624-3p Promotes Esophageal Squamous Cell Carcinoma Progression via Targeting Phosphatase and Tensin Homologue.
Jia H, Wang H, Xia F, Sun Y, Liu H, Yan L, Li S, Jiang D, Xu M. Jia H, et al. DNA Cell Biol. 2020 Nov 4. doi: 10.1089/dna.2020.6101. Online ahead of print. DNA Cell Biol. 2020. PMID: 33147068
The emerging role of miRNA as regulators in esophageal squamous cell carcinoma (ESCC) progression has aroused great attention recently. In this study, the effects of miR-624-3p in ESCC progression were explored through cell proliferation, colony formation, cell …
The emerging role of miRNA as regulators in esophageal squamous cell carcinoma (ESCC) progression has aroused great attention recentl …
Immune and Circulating Tumor DNA Profiling After Radiation Treatment for Oligometastatic Non-Small Cell Lung Cancer: Translational Correlatives from a Mature Randomized Phase II Trial.
Tang C, Lee WC, Reuben A, Chang L, Tran H, Little L, Gumbs C, Wargo J, Futreal A, Liao Z, Xia X, Yi X, Swisher SG, Heymach JV, Gomez D, Zhang J. Tang C, et al. Int J Radiat Oncol Biol Phys. 2020 Feb 1;106(2):349-357. doi: 10.1016/j.ijrobp.2019.10.038. Epub 2019 Oct 31. Int J Radiat Oncol Biol Phys. 2020. PMID: 31678224 Clinical Trial.
PURPOSE: NCT01725165 was a phase II prospective trial in which patients with non-small cell lung cancer were randomized to local consolidative therapy (LCT) versus maintenance therapy or observation (MT/O). ...All patients who underwent LCT and were included in this analys …
PURPOSE: NCT01725165 was a phase II prospective trial in which patients with non-small cell lung cancer were randomized to local cons …
TADsplimer reveals splits and mergers of topologically associating domains for epigenetic regulation of transcription.
Wang G, Meng Q, Xia B, Zhang S, Lv J, Zhao D, Li Y, Wang X, Zhang L, Cooke JP, Cao Q, Chen K. Wang G, et al. Genome Biol. 2020 Apr 2;21(1):84. doi: 10.1186/s13059-020-01992-7. Genome Biol. 2020. PMID: 32241291 Free PMC article.
TADsplimer recaptures splits and mergers of TADs with high accuracy in simulation analyses and defines hundreds of TAD splits and mergers between pairs of different cell types, such as endothelial cells and fibroblasts. Our work reveals a key role for TAD remodeling in epi …
TADsplimer recaptures splits and mergers of TADs with high accuracy in simulation analyses and defines hundreds of TAD splits and mergers be …
The novel insight into the outcomes of CRISPR/Cas9 editing intra- and inter-species.
Chang J, Chen X, Zhang T, Wang R, Wang A, Lan X, Zhou Y, Ma S, Xia Q. Chang J, et al. Int J Biol Macromol. 2020 Nov 15;163:711-717. doi: 10.1016/j.ijbiomac.2020.07.039. Epub 2020 Jul 8. Int J Biol Macromol. 2020. PMID: 32652159
We also found that within a species, indel patterns are sequence dependent, wherein deletions between two adjacent micro-homology sequences were the most frequently observed mutations in the repair spectrum. These results suggested the species differences in DNA repair pro …
We also found that within a species, indel patterns are sequence dependent, wherein deletions between two adjacent micro-homology sequences …
23 results