Xu C - Search Results

1

Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.

Gres AT, Kirby KA, McFadden WM, Du H, Liu D, Xu C, Bryer AJ, Perilla JR, Shi J, Aiken C, Fu X, Zhang P, Francis AC, Melikyan GB, Sarafianos SG. Gres AT, et al. Among authors: xu c. Nat Commun. 2023 Sep 12;14(1):5614. doi: 10.1038/s41467-023-41197-7. Nat Commun. 2023. PMID: 37699872 Free PMC article.

2

Inositol phosphates are assembly co-factors for HIV-1.

Dick RA, Zadrozny KK, Xu C, Schur FKM, Lyddon TD, Ricana CL, Wagner JM, Perilla JR, Ganser-Pornillos BK, Johnson MC, Pornillos O, Vogt VM. Dick RA, et al. Among authors: xu c. Nature. 2018 Aug;560(7719):509-512. doi: 10.1038/s41586-018-0396-4. Epub 2018 Aug 1. Nature. 2018. PMID: 30069050 Free PMC article.

3

MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid.

Smaga SS, Xu C, Summers BJ, Digianantonio KM, Perilla JR, Xiong Y. Smaga SS, et al. Among authors: xu c. Structure. 2019 Aug 6;27(8):1234-1245.e5. doi: 10.1016/j.str.2019.04.015. Epub 2019 May 30. Structure. 2019. PMID: 31155311 Free PMC article.

4

FEZ1 Is Recruited to a Conserved Cofactor Site on Capsid to Promote HIV-1 Trafficking.

Huang PT, Summers BJ, Xu C, Perilla JR, Malikov V, Naghavi MH, Xiong Y. Huang PT, et al. Among authors: xu c. Cell Rep. 2019 Aug 27;28(9):2373-2385.e7. doi: 10.1016/j.celrep.2019.07.079. Epub 2019 Aug 14. Cell Rep. 2019. PMID: 31422020 Free PMC article.

5

Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis.

Xu C, Fischer DK, Rankovic S, Li W, Dick RA, Runge B, Zadorozhnyi R, Ahn J, Aiken C, Polenova T, Engelman AN, Ambrose Z, Rousso I, Perilla JR. Xu C, et al. PLoS Biol. 2020 Dec 17;18(12):e3001015. doi: 10.1371/journal.pbio.3001015. eCollection 2020 Dec. PLoS Biol. 2020. PMID: 33332391 Free PMC article.

6

Magic angle spinning NMR structure of human cofilin-2 assembled on actin filaments reveals isoform-specific conformation and binding mode.

Kraus J, Russell RW, Kudryashova E, Xu C, Katyal N, Perilla JR, Kudryashov DS, Polenova T. Kraus J, et al. Among authors: xu c. Nat Commun. 2022 Apr 19;13(1):2114. doi: 10.1038/s41467-022-29595-9. Nat Commun. 2022. PMID: 35440100 Free PMC article.

7

The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores.

Shen Q, Kumari S, Xu C, Jang S, Shi J, Burdick RC, Levintov L, Xiong Q, Wu C, Devarkar SC, Tian T, Tripler TN, Hu Y, Yuan S, Temple J, Feng Q, Lusk CP, Aiken C, Engelman AN, Perilla JR, Pathak VK, Lin C, Xiong Y. Shen Q, et al. Among authors: xu c. Proc Natl Acad Sci U S A. 2023 Mar 28;120(13):e2202815120. doi: 10.1073/pnas.2202815120. Epub 2023 Mar 21. Proc Natl Acad Sci U S A. 2023. PMID: 36943880 Free PMC article.

8

Dynamic regulation of HIV-1 capsid interaction with the restriction factor TRIM5α identified by magic-angle spinning NMR and molecular dynamics simulations.

Quinn CM, Wang M, Fritz MP, Runge B, Ahn J, Xu C, Perilla JR, Gronenborn AM, Polenova T. Quinn CM, et al. Among authors: xu c. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):11519-11524. doi: 10.1073/pnas.1800796115. Epub 2018 Oct 17. Proc Natl Acad Sci U S A. 2018. PMID: 30333189 Free PMC article.

9

HIV-1 mutants that escape the cytotoxic T-lymphocytes are defective in viral DNA integration.

Balasubramaniam M, Davids BO, Bryer A, Xu C, Thapa S, Shi J, Aiken C, Pandhare J, Perilla JR, Dash C. Balasubramaniam M, et al. Among authors: xu c. PNAS Nexus. 2022 May 20;1(2):pgac064. doi: 10.1093/pnasnexus/pgac064. eCollection 2022 May. PNAS Nexus. 2022. PMID: 35719891 Free PMC article.

10

Molecular determinants of Ebola nucleocapsid stability from molecular dynamics simulations.

Xu C, Katyal N, Nesterova T, Perilla JR. Xu C, et al. J Chem Phys. 2020 Oct 21;153(15):155102. doi: 10.1063/5.0021491. J Chem Phys. 2020. PMID: 33092380 Free PMC article.

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