Xu HE - Search Results

1

Synthesis and biological activity of L-tyrosine-based PPARgamma agonists with reduced molecular weight.

Liu KG, Lambert MH, Ayscue AH, Henke BR, Leesnitzer LM, Oliver WR Jr, Plunket KD, Xu HE, Sternbach DD, Willson TM. Liu KG, et al. Among authors: xu he. Bioorg Med Chem Lett. 2001 Dec 17;11(24):3111-3. doi: 10.1016/s0960-894x(01)00649-7. Bioorg Med Chem Lett. 2001. PMID: 11720854

2

Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)--synthesis and biological activity.

Sznaidman ML, Haffner CD, Maloney PR, Fivush A, Chao E, Goreham D, Sierra ML, LeGrumelec C, Xu HE, Montana VG, Lambert MH, Willson TM, Oliver WR Jr, Sternbach DD. Sznaidman ML, et al. Among authors: xu he. Bioorg Med Chem Lett. 2003 May 5;13(9):1517-21. doi: 10.1016/s0960-894x(03)00207-5. Bioorg Med Chem Lett. 2003. PMID: 12699745

3

Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha.

Xu HE, Stanley TB, Montana VG, Lambert MH, Shearer BG, Cobb JE, McKee DD, Galardi CM, Plunket KD, Nolte RT, Parks DJ, Moore JT, Kliewer SA, Willson TM, Stimmel JB. Xu HE, et al. Nature. 2002 Feb 14;415(6873):813-7. doi: 10.1038/415813a. Nature. 2002. PMID: 11845213

4

Structure-based design of potent retinoid X receptor alpha agonists.

Haffner CD, Lenhard JM, Miller AB, McDougald DL, Dwornik K, Ittoop OR, Gampe RT Jr, Xu HE, Blanchard S, Montana VG, Consler TG, Bledsoe RK, Ayscue A, Croom D. Haffner CD, et al. Among authors: xu he. J Med Chem. 2004 Apr 8;47(8):2010-29. doi: 10.1021/jm030565g. J Med Chem. 2004. PMID: 15056000

5

Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors.

Gampe RT Jr, Montana VG, Lambert MH, Miller AB, Bledsoe RK, Milburn MV, Kliewer SA, Willson TM, Xu HE. Gampe RT Jr, et al. Among authors: xu he. Mol Cell. 2000 Mar;5(3):545-55. doi: 10.1016/s1097-2765(00)80448-7. Mol Cell. 2000. PMID: 10882139 Free article.

6

Peroxisome proliferator-activated receptors: from genes to physiology.

Kliewer SA, Xu HE, Lambert MH, Willson TM. Kliewer SA, et al. Among authors: xu he. Recent Prog Horm Res. 2001;56:239-63. doi: 10.1210/rp.56.1.239. Recent Prog Horm Res. 2001. PMID: 11237216 Review.

7

A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport.

Oliver WR Jr, Shenk JL, Snaith MR, Russell CS, Plunket KD, Bodkin NL, Lewis MC, Winegar DA, Sznaidman ML, Lambert MH, Xu HE, Sternbach DD, Kliewer SA, Hansen BC, Willson TM. Oliver WR Jr, et al. Among authors: xu he. Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5306-11. doi: 10.1073/pnas.091021198. Epub 2001 Apr 17. Proc Natl Acad Sci U S A. 2001. PMID: 11309497 Free PMC article.

8

Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors.

Xu HE, Lambert MH, Montana VG, Plunket KD, Moore LB, Collins JL, Oplinger JA, Kliewer SA, Gampe RT Jr, McKee DD, Moore JT, Willson TM. Xu HE, et al. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13919-24. doi: 10.1073/pnas.241410198. Epub 2001 Nov 6. Proc Natl Acad Sci U S A. 2001. PMID: 11698662 Free PMC article.

9

Subtype specific effects of peroxisome proliferator-activated receptor ligands on corepressor affinity.

Stanley TB, Leesnitzer LM, Montana VG, Galardi CM, Lambert MH, Holt JA, Xu HE, Moore LB, Blanchard SG, Stimmel JB. Stanley TB, et al. Among authors: xu he. Biochemistry. 2003 Aug 12;42(31):9278-87. doi: 10.1021/bi034472c. Biochemistry. 2003. PMID: 12899614

10

Molecular recognition of fatty acids by peroxisome proliferator-activated receptors.

Xu HE, Lambert MH, Montana VG, Parks DJ, Blanchard SG, Brown PJ, Sternbach DD, Lehmann JM, Wisely GB, Willson TM, Kliewer SA, Milburn MV. Xu HE, et al. Mol Cell. 1999 Mar;3(3):397-403. doi: 10.1016/s1097-2765(00)80467-0. Mol Cell. 1999. PMID: 10198642 Free article.

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