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Year Number of Results
2003 1
2004 2
2006 1
2007 3
2008 1
2009 2
2010 2
2012 10
2013 11
2014 18
2015 13
2016 17
2017 17
2018 18
2019 19
2020 25
2021 22
2022 19
2023 24
2024 12

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203 results

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Page 1
YWHAE promotes proliferation, metastasis, and chemoresistance in breast cancer cells.
Yang YF, Lee YC, Wang YY, Wang CH, Hou MF, Yuan SF. Yang YF, et al. Kaohsiung J Med Sci. 2019 Jul;35(7):408-416. doi: 10.1002/kjm2.12075. Epub 2019 Apr 18. Kaohsiung J Med Sci. 2019. PMID: 31001932 Free article.
However, the clinical implication and function of YWHAE in breast cancer remains unclear. In this study, we investigated the prognostic value of the YWHAE in human breast cancer. Immunohistochemistry was used to analyze YWHAE expression in breas …
However, the clinical implication and function of YWHAE in breast cancer remains unclear. In this study, we investigated the p …
A genome-wide CRISPR-Cas9 knockout screen identifies novel PARP inhibitor resistance genes in prostate cancer.
Ipsen MB, Sørensen EMG, Thomsen EA, Weiss S, Haldrup J, Dalby A, Palmfeldt J, Bross P, Rasmussen M, Fredsøe J, Klingenberg S, Jochumsen MR, Bouchelouche K, Ulhøi BP, Borre M, Mikkelsen JG, Sørensen KD. Ipsen MB, et al. Oncogene. 2022 Sep;41(37):4271-4281. doi: 10.1038/s41388-022-02427-2. Epub 2022 Aug 6. Oncogene. 2022. PMID: 35933519
DNA repair gene mutations are frequent in castration-resistant prostate cancer (CRPC), suggesting eligibility for poly(ADP-ribose) polymerase inhibitor (PARPi) treatment. ...For validation, we generated multiple knockout populations/clones per gene in C4 and/or LNCaP CRPC …
DNA repair gene mutations are frequent in castration-resistant prostate cancer (CRPC), suggesting eligibility for poly(ADP-ribose) po …
KRAS, YWHAE, SP1 and MSRA as biomarkers in endometrial cancer.
Yang Y, Sang ZY, Ma J, Zhu YP, Wu SF. Yang Y, et al. Transl Cancer Res. 2021 Mar;10(3):1295-1312. doi: 10.21037/tcr-20-2969. Transl Cancer Res. 2021. PMID: 35116456 Free PMC article.
Gene Ontology (GO) annotations and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were associated with the binding region, biological regulation, endocrine resistance, estrogen signaling, choline metabolism in cancer and human cytomegalovirus infection. Furthermor …
Gene Ontology (GO) annotations and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were associated with the binding region, biologic …
Genetic variation of YWHAE gene-"Switch" of disease control.
Jin X, Dai M, Zhou Y. Jin X, et al. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2022 Jan 28;47(1):101-108. doi: 10.11817/j.issn.1672-7347.2022.210394. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2022. PMID: 35545369 Free PMC article. Chinese, English.
Overexpression of YWHAE in breast cancer can increase the ability of proliferation, migration and invasion of breast cancer cells. ...Overexpression of YWHAE in breast cancer can increase the ability of proliferation, migration and invasion of b …
Overexpression of YWHAE in breast cancer can increase the ability of proliferation, migration and invasion of breast cancer …
miR-29b-3p inhibits 22Rv1 prostate cancer cell proliferation through the YWHAE/BCL-2 regulatory axis.
Zhao J, Ma X, Xu H. Zhao J, et al. Oncol Lett. 2022 Jul 1;24(2):289. doi: 10.3892/ol.2022.13409. eCollection 2022 Aug. Oncol Lett. 2022. PMID: 35928803 Free PMC article.
Prostate cancer (PCa) is one of the most common malignant tumours in the world and seriously affects health of men. ...Using bioinformatics and a double luciferase system assay, it was confirmed that miR-29b-3p can target YWHAE 3'untranslated region and affect the e …
Prostate cancer (PCa) is one of the most common malignant tumours in the world and seriously affects health of men. ...Using bioinfor …
YWHAE as an HE4 interacting protein can influence the malignant behaviour of ovarian cancer by regulating the PI3K/AKT and MAPK pathways.
Li X, Wang C, Wang S, Hu Y, Jin S, Liu O, Gou R, Nie X, Liu J, Lin B. Li X, et al. Cancer Cell Int. 2021 Jun 9;21(1):302. doi: 10.1186/s12935-021-01989-7. Cancer Cell Int. 2021. PMID: 34107979 Free PMC article.
Moreover, YWHAE upregulation was associated with advanced stages of ovarian cancer and poor patient prognosis. ...Furthermore, YWHAE and its downstream pathways may represent new therapeutic targets for ovarian cancer....
Moreover, YWHAE upregulation was associated with advanced stages of ovarian cancer and poor patient prognosis. ...Furthermore, …
[NKD1 promotes glucose uptake in colon cancer cells by activating YWHAE transcription].
Liu Q, Dai Y, Yu H, Shen Y, Deng J, Lu W, Jin J. Liu Q, et al. Nan Fang Yi Ke Da Xue Xue Bao. 2023 Apr 20;43(4):585-589. doi: 10.12122/j.issn.1673-4254.2023.04.11. Nan Fang Yi Ke Da Xue Xue Bao. 2023. PMID: 37202194 Free PMC article. Chinese.

Immunofluorescence assay demonstrated the binding of NKD1 and YWHAE proteins in colon cancer cells. NKD1 knockout significantly reduced glucose uptake in colon cancer cells (P < 0.01), while YWHAE overexpression restored the glucose uptake in NKD1-k

…
Immunofluorescence assay demonstrated the binding of NKD1 and YWHAE proteins in colon cancer cells. NKD1 knockout significantl …
Comprehensive analysis of the function of helicobacter-associated ferroptosis gene YWHAE in gastric cancer through multi-omics integration, molecular docking, and machine learning.
Liu D, Peng J, Xie J, Xie Y. Liu D, et al. Apoptosis. 2024 Apr;29(3-4):439-456. doi: 10.1007/s10495-023-01916-3. Epub 2023 Nov 24. Apoptosis. 2024. PMID: 38001345
Our findings demonstrated that the YWHAE gene exhibits high expression in both H. pylori-associated gastritis and gastric cancer. Pan-cancer analysis revealed elevated expression of YWHAE in several cancer types compared to normal tissues. ...
Our findings demonstrated that the YWHAE gene exhibits high expression in both H. pylori-associated gastritis and gastric cancer …
YWHAE silencing induces cell proliferation, invasion and migration through the up-regulation of CDC25B and MYC in gastric cancer cells: new insights about YWHAE role in the tumor development and metastasis process.
Leal MF, Ribeiro HF, Rey JA, Pinto GR, Smith MC, Moreira-Nunes CA, Assumpção PP, Lamarão LM, Calcagno DQ, Montenegro RC, Burbano RR. Leal MF, et al. Oncotarget. 2016 Dec 20;7(51):85393-85410. doi: 10.18632/oncotarget.13381. Oncotarget. 2016. PMID: 27863420 Free PMC article.
We previously observed reduced YWHAE (14-3-3epsilon) protein expression in a small set of gastric cancer samples. ...Thus, we aimed to evaluate the relationship among YWHAE, CDC25B, and MYC in vitro and in vivo. For this, we analyzed the YWHAE, CDC25B, …
We previously observed reduced YWHAE (14-3-3epsilon) protein expression in a small set of gastric cancer samples. ...Thus, we …
203 results