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Adventitial CXCL1/G-CSF expression in response to acute aortic dissection triggers local neutrophil recruitment and activation leading to aortic rupture.
Anzai A, Shimoda M, Endo J, Kohno T, Katsumata Y, Matsuhashi T, Yamamoto T, Ito K, Yan X, Shirakawa K, Shimizu-Hirota R, Yamada Y, Ueha S, Shinmura K, Okada Y, Fukuda K, Sano M. Anzai A, et al. Among authors: yamamoto t. Circ Res. 2015 Feb 13;116(4):612-23. doi: 10.1161/CIRCRESAHA.116.304918. Epub 2015 Jan 6. Circ Res. 2015. PMID: 25563839
Cardiac Sirt1 mediates the cardioprotective effect of caloric restriction by suppressing local complement system activation after ischemia-reperfusion.
Yamamoto T, Tamaki K, Shirakawa K, Ito K, Yan X, Katsumata Y, Anzai A, Matsuhashi T, Endo J, Inaba T, Tsubota K, Sano M, Fukuda K, Shinmura K. Yamamoto T, et al. Am J Physiol Heart Circ Physiol. 2016 Apr 15;310(8):H1003-14. doi: 10.1152/ajpheart.00676.2015. Epub 2016 Feb 12. Am J Physiol Heart Circ Physiol. 2016. PMID: 26873964 Free article.
We previously found the essential roles of endothelial nitric oxide synthase in the development of CR-induced cardioprotection and Sirt1 activation during CR (Shinmura K, Tamaki K, Ito K, Yan X, Yamamoto T, Katsumata Y, Matsuhashi T, Sano M, Fukuda K, Suemats …
We previously found the essential roles of endothelial nitric oxide synthase in the development of CR-induced cardioprotection and Sirt1 act …
Indispensable role of endothelial nitric oxide synthase in caloric restriction-induced cardioprotection against ischemia-reperfusion injury.
Shinmura K, Tamaki K, Ito K, Yan X, Yamamoto T, Katsumata Y, Matsuhashi T, Sano M, Fukuda K, Suematsu M, Ishii I. Shinmura K, et al. Among authors: yamamoto t. Am J Physiol Heart Circ Physiol. 2015 Apr 15;308(8):H894-903. doi: 10.1152/ajpheart.00333.2014. Epub 2015 Feb 13. Am J Physiol Heart Circ Physiol. 2015. PMID: 25681423 Free article.
Activation of pyruvate dehydrogenase by dichloroacetate has the potential to induce epigenetic remodeling in the heart.
Matsuhashi T, Hishiki T, Zhou H, Ono T, Kaneda R, Iso T, Yamaguchi A, Endo J, Katsumata Y, Atsushi A, Yamamoto T, Shirakawa K, Yan X, Shinmura K, Suematsu M, Fukuda K, Sano M. Matsuhashi T, et al. Among authors: yamamoto t. J Mol Cell Cardiol. 2015 May;82:116-24. doi: 10.1016/j.yjmcc.2015.02.021. Epub 2015 Mar 2. J Mol Cell Cardiol. 2015. PMID: 25744081
Negative legacy of obesity.
Shirakawa K, Endo J, Katsumata Y, Yamamoto T, Kataoka M, Isobe S, Yoshida N, Fukuda K, Sano M. Shirakawa K, et al. Among authors: yamamoto t. PLoS One. 2017 Oct 26;12(10):e0186303. doi: 10.1371/journal.pone.0186303. eCollection 2017. PLoS One. 2017. PMID: 29073165 Free PMC article.
Pressure overload inhibits glucocorticoid receptor transcriptional activity in cardiomyocytes and promotes pathological cardiac hypertrophy.
Matsuhashi T, Endo J, Katsumata Y, Yamamoto T, Shimizu N, Yoshikawa N, Kataoka M, Isobe S, Moriyama H, Goto S, Fukuda K, Tanaka H, Sano M. Matsuhashi T, et al. Among authors: yamamoto t. J Mol Cell Cardiol. 2019 May;130:122-130. doi: 10.1016/j.yjmcc.2019.03.019. Epub 2019 Apr 1. J Mol Cell Cardiol. 2019. PMID: 30946837
Adrenal cortex hypoxia modulates aldosterone production in heart failure.
Yamashita K, Ito K, Endo J, Matsuhashi T, Katsumata Y, Yamamoto T, Shirakawa K, Isobe S, Kataoka M, Yoshida N, Goto S, Moriyama H, Kitakata H, Mitani F, Fukuda K, Goda N, Ichihara A, Sano M. Yamashita K, et al. Among authors: yamamoto t. Biochem Biophys Res Commun. 2020 Mar 26;524(1):184-189. doi: 10.1016/j.bbrc.2020.01.088. Epub 2020 Jan 23. Biochem Biophys Res Commun. 2020. PMID: 31982132 Free article.
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