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MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition.
Vande Walle L, Stowe IB, Šácha P, Lee BL, Demon D, Fossoul A, Van Hauwermeiren F, Saavedra PHV, Šimon P, Šubrt V, Kostka L, Stivala CE, Pham VC, Staben ST, Yamazoe S, Konvalinka J, Kayagaki N, Lamkanfi M. Vande Walle L, et al. Among authors: yamazoe s. PLoS Biol. 2019 Sep 16;17(9):e3000354. doi: 10.1371/journal.pbio.3000354. eCollection 2019 Sep. PLoS Biol. 2019. PMID: 31525186 Free PMC article.
Correction: MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition.
Walle LV, Stowe IB, Šácha P, Lee BL, Demon D, Fossoul A, Van Hauwermeiren F, Saavedra PHV, Šimon P, Šubr V, Kostka L, Stivala CE, Pham VC, Staben ST, Yamazoe S, Konvalinka J, Kayagaki N, Lamkanfi M. Walle LV, et al. Among authors: yamazoe s. PLoS Biol. 2019 Oct 16;17(10):e3000529. doi: 10.1371/journal.pbio.3000529. eCollection 2019 Oct. PLoS Biol. 2019. PMID: 31618263 Free PMC article.
Identifying transcriptional programs underlying cancer drug response with TraCe-seq.
Chang MT, Shanahan F, Nguyen TTT, Staben ST, Gazzard L, Yamazoe S, Wertz IE, Piskol R, Yang YA, Modrusan Z, Haley B, Evangelista M, Malek S, Foster SA, Ye X. Chang MT, et al. Among authors: yamazoe s. Nat Biotechnol. 2022 Jan;40(1):86-93. doi: 10.1038/s41587-021-01005-3. Epub 2021 Sep 16. Nat Biotechnol. 2022. PMID: 34531539
Ternary complex dissociation kinetics contribute to mutant-selective EGFR degradation.
Rosenberg SC, Shanahan F, Yamazoe S, Kschonsak M, Zeng YJ, Lee J, Plise E, Yen I, Rose CM, Quinn JG, Gazzard LJ, Walters BT, Kirkpatrick DS, Staben ST, Foster SA, Malek S. Rosenberg SC, et al. Among authors: yamazoe s. Cell Chem Biol. 2023 Feb 8:S2451-9456(23)00030-2. doi: 10.1016/j.chembiol.2023.01.007. Online ahead of print. Cell Chem Biol. 2023. PMID: 36773603 Free article.
Primary Amine Tethered Small Molecules Promote the Degradation of X-Linked Inhibitor of Apoptosis Protein.
den Besten W, Verma K, Yamazoe S, Blaquiere N, Phung W, Izrael-Tomasevic A, Mulvihill MM, Helgason E, Prakash S, Goncharov T, Vucic D, Dueber E, Fairbrother WJ, Wertz I, Yu K, Staben ST. den Besten W, et al. Among authors: yamazoe s. J Am Chem Soc. 2021 Jul 21;143(28):10571-10575. doi: 10.1021/jacs.1c05269. Epub 2021 Jul 8. J Am Chem Soc. 2021. PMID: 34236858
Humanization of a strategic CD3 epitope enables evaluation of clinical T-cell engagers in a fully immunocompetent in vivo model.
Zorn JA, Wheeler ML, Barnes RM, Kaberna J, Morishige W, Harris M, Huang RY, Lohre J, Chang YC, Chau B, Powers K, Schindler I, Neradugomma N, Thomas W, Liao X, Zhou Y, West SM, Wang F, Kotapati S, Chen G, Yamazoe S, Kosenko A, Dollinger G, Sproul T, Rajpal A, Strop P. Zorn JA, et al. Among authors: yamazoe s. Sci Rep. 2022 Mar 3;12(1):3530. doi: 10.1038/s41598-022-06953-7. Sci Rep. 2022. PMID: 35241687 Free PMC article.
209 results