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The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to hyperactivate AKT and confer resistance to AKT inhibitors.
Lin A, Hu Q, Li C, Xing Z, Ma G, Wang C, Li J, Ye Y, Yao J, Liang K, Wang S, Park PK, Marks JR, Zhou Y, Zhou J, Hung MC, Liang H, Hu Z, Shen H, Hawke DH, Han L, Zhou Y, Lin C, Yang L. Lin A, et al. Among authors: yang l. Nat Cell Biol. 2017 Mar;19(3):238-251. doi: 10.1038/ncb3473. Epub 2017 Feb 20. Nat Cell Biol. 2017. PMID: 28218907 Free PMC article.
Signaling to the DEAD box--regulation of DEAD-box p68 RNA helicase by protein phosphorylations.
Yang L, Lin C, Liu ZR. Yang L, et al. Cell Signal. 2005 Dec;17(12):1495-504. doi: 10.1016/j.cellsig.2005.03.008. Cell Signal. 2005. PMID: 15927448
We previously observed that bacterially expressed his-p68 was phosphorylated at multiple sites including serine/threonine and tyrosine [L. Yang, Z.R. Liu, Protein Expr. Purif., 35: 327]. Here we report that p68 RNA helicase is phosphorylated at tyrosine residue(s) i …
We previously observed that bacterially expressed his-p68 was phosphorylated at multiple sites including serine/threonine and tyrosine [L
A lincRNA switch for embryonic stem cell fate.
Yang L, Lin C, Rosenfeld MG. Yang L, et al. Cell Res. 2011 Dec;21(12):1646-8. doi: 10.1038/cr.2011.166. Epub 2011 Oct 25. Cell Res. 2011. PMID: 22025254 Free PMC article. No abstract available.
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