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Rational design of chimeric antigen receptor T cells against glypican 3 decouples toxicity from therapeutic efficacy.
Giardino Torchia ML, Gilbreth R, Merlino A, Sult E, Monks N, Chesebrough J, Tammali R, Chu N, Tong J, Meekin J 3rd, Schifferli K, Vashisht K, DaCosta K, Clarke L, Gesse C, Yao XT, Bridges C, Moody G. Giardino Torchia ML, et al. Among authors: yao xt. Cytotherapy. 2022 Jul;24(7):720-732. doi: 10.1016/j.jcyt.2022.03.008. Epub 2022 May 12. Cytotherapy. 2022. PMID: 35570170 Free article.
Simultaneous targeting of TNF and Ang2 with a novel bispecific antibody enhances efficacy in an in vivo model of arthritis.
Kanakaraj P, Puffer BA, Yao XT, Kankanala S, Boyd E, Shah RR, Wang G, Patel D, Krishnamurthy R, Kaithamana S, Smith RG, LaFleur DW, Barbas CF 3rd, Hilbert DM, Kiener PA, Roschke VV. Kanakaraj P, et al. Among authors: yao xt. MAbs. 2012 Sep-Oct;4(5):600-13. doi: 10.4161/mabs.21227. Epub 2012 Aug 6. MAbs. 2012. PMID: 22864384 Free PMC article.
Monoclonal antibody therapeutics with up to five specificities: functional enhancement through fusion of target-specific peptides.
LaFleur DW, Abramyan D, Kanakaraj P, Smith RG, Shah RR, Wang G, Yao XT, Kankanala S, Boyd E, Zaritskaya L, Nam V, Puffer BA, Buasen P, Kaithamana S, Burnette AF, Krishnamurthy R, Patel D, Roschke VV, Kiener PA, Hilbert DM, Barbas CF 3rd. LaFleur DW, et al. Among authors: yao xt. MAbs. 2013 Mar-Apr;5(2):208-18. doi: 10.4161/mabs.23043. MAbs. 2013. PMID: 23575268 Free PMC article.
29 results