Yates CM - Search Results

1

Enantioselective cyanation/Brook rearrangement/C-acylation reactions of acylsilanes catalyzed by chiral metal alkoxides.

Nicewicz DA, Yates CM, Johnson JS. Nicewicz DA, et al. Among authors: yates cm. J Org Chem. 2004 Oct 1;69(20):6548-55. doi: 10.1021/jo049164e. J Org Chem. 2004. PMID: 15387576

2

Metallophosphite-induced nucleophilic acylation of alpha,beta-unsaturated amides: facilitated catalysis by a diastereoselective retro [1,4] Brook rearrangement.

Nahm MR, Linghu X, Potnick JR, Yates CM, White PS, Johnson JS. Nahm MR, et al. Among authors: yates cm. Angew Chem Int Ed Engl. 2005 Apr 15;44(16):2377-9. doi: 10.1002/anie.200462795. Angew Chem Int Ed Engl. 2005. PMID: 15761891 Free PMC article. No abstract available.

3

Catalytic asymmetric acylation of (silyloxy)nitrile anions.

Nicewicz DA, Yates CM, Johnson JS. Nicewicz DA, et al. Among authors: yates cm. Angew Chem Int Ed Engl. 2004 May 10;43(20):2652-5. doi: 10.1002/anie.200353354. Angew Chem Int Ed Engl. 2004. PMID: 18629980 No abstract available.

4

Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines.

Liu F, Barsyte-Lovejoy D, Allali-Hassani A, He Y, Herold JM, Chen X, Yates CM, Frye SV, Brown PJ, Huang J, Vedadi M, Arrowsmith CH, Jin J. Liu F, et al. Among authors: yates cm. J Med Chem. 2011 Sep 8;54(17):6139-50. doi: 10.1021/jm200903z. Epub 2011 Aug 5. J Med Chem. 2011. PMID: 21780790 Free PMC article.

5

Structure guided design of 5-arylindazole glucocorticoid receptor agonists and antagonists.

Yates CM, Brown PJ, Stewart EL, Patten C, Austin RJ, Holt JA, Maglich JM, Angell DC, Sasse RZ, Taylor SJ, Uings IJ, Trump RP. Yates CM, et al. J Med Chem. 2010 Jun 10;53(11):4531-44. doi: 10.1021/jm100447c. J Med Chem. 2010. PMID: 20469868

6

Design and optimization of highly-selective fungal CYP51 inhibitors.

Hoekstra WJ, Garvey EP, Moore WR, Rafferty SW, Yates CM, Schotzinger RJ. Hoekstra WJ, et al. Among authors: yates cm. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3455-8. doi: 10.1016/j.bmcl.2014.05.068. Epub 2014 Jun 9. Bioorg Med Chem Lett. 2014. PMID: 24948565

7

Design and optimization of highly-selective, broad spectrum fungal CYP51 inhibitors.

Yates CM, Garvey EP, Shaver SR, Schotzinger RJ, Hoekstra WJ. Yates CM, et al. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3243-3248. doi: 10.1016/j.bmcl.2017.06.037. Epub 2017 Jun 15. Bioorg Med Chem Lett. 2017. PMID: 28651982

8

Development of Highly Selective Pyrimidine-Based Aldosterone Synthase (CYP11B2) Inhibitors.

Sparks SM, Danger DP, Hoekstra WJ, Leesnitzer T, Schotzinger RJ, Yates CM, Becherer JD. Sparks SM, et al. Among authors: yates cm. ACS Med Chem Lett. 2019 Jun 7;10(7):1056-1060. doi: 10.1021/acsmedchemlett.9b00152. eCollection 2019 Jul 11. ACS Med Chem Lett. 2019. PMID: 31312408 Free PMC article.

9

The novel fungal CYP51 inhibitor VT-1598 is efficacious alone and in combination with liposomal amphotericin B in a murine model of cryptococcal meningitis.

Garvey EP, Sharp AD, Warn PA, Yates CM, Schotzinger RJ. Garvey EP, et al. Among authors: yates cm. J Antimicrob Chemother. 2018 Oct 1;73(10):2815-2822. doi: 10.1093/jac/dky242. J Antimicrob Chemother. 2018. PMID: 29947783

10

The novel fungal CYP51 inhibitor VT-1598 displays classic dose-dependent antifungal activity in murine models of invasive aspergillosis.

Garvey EP, Sharp AD, Warn PA, Yates CM, Atari M, Thomas S, Schotzinger RJ. Garvey EP, et al. Among authors: yates cm. Med Mycol. 2020 Jun 1;58(4):505-513. doi: 10.1093/mmy/myz092. Med Mycol. 2020. PMID: 32476008

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