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The CD3 conformational change in the γδ T cell receptor is not triggered by antigens but can be enforced to enhance tumor killing.
Dopfer EP, Hartl FA, Oberg HH, Siegers GM, Yousefi OS, Kock S, Fiala GJ, Garcillán B, Sandstrom A, Alarcón B, Regueiro JR, Kabelitz D, Adams EJ, Minguet S, Wesch D, Fisch P, Schamel WWA. Dopfer EP, et al. Among authors: yousefi os. Cell Rep. 2014 Jun 12;7(5):1704-1715. doi: 10.1016/j.celrep.2014.04.049. Epub 2014 May 22. Cell Rep. 2014. PMID: 24857663 Free article.
A Cholesterol-Based Allostery Model of T Cell Receptor Phosphorylation.
Swamy M, Beck-Garcia K, Beck-Garcia E, Hartl FA, Morath A, Yousefi OS, Dopfer EP, Molnár E, Schulze AK, Blanco R, Borroto A, Martín-Blanco N, Alarcon B, Höfer T, Minguet S, Schamel WW. Swamy M, et al. Among authors: yousefi os. Immunity. 2016 May 17;44(5):1091-101. doi: 10.1016/j.immuni.2016.04.011. Immunity. 2016. PMID: 27192576 Free article.
Optogenetic control of integrin-matrix interaction.
Baaske J, Mühlhäuser WWD, Yousefi OS, Zanner S, Radziwill G, Hörner M, Schamel WWA, Weber W. Baaske J, et al. Among authors: yousefi os. Commun Biol. 2019 Jan 8;2:15. doi: 10.1038/s42003-018-0264-7. eCollection 2019. Commun Biol. 2019. PMID: 30652127 Free PMC article.
Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function.
Hartl FA, Beck-Garcìa E, Woessner NM, Flachsmann LJ, Cárdenas RMV, Brandl SM, Taromi S, Fiala GJ, Morath A, Mishra P, Yousefi OS, Zimmermann J, Hoefflin N, Köhn M, Wöhrl BM, Zeiser R, Schweimer K, Günther S, Schamel WW, Minguet S. Hartl FA, et al. Among authors: yousefi os. Nat Immunol. 2020 Aug;21(8):902-913. doi: 10.1038/s41590-020-0732-3. Epub 2020 Jul 20. Nat Immunol. 2020. PMID: 32690949
Author Correction: Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function.
Hartl FA, Beck-Garcìa E, Woessner NM, Flachsmann LJ, Cárdenas RMV, Brandl SM, Taromi S, Fiala GJ, Morath A, Mishra P, Yousefi OS, Zimmermann J, Hoefflin N, Köhn M, Wöhrl BM, Zeiser R, Schweimer K, Günther S, Schamel WW, Minguet S. Hartl FA, et al. Among authors: yousefi os. Nat Immunol. 2021 Jan;22(1):100-101. doi: 10.1038/s41590-020-00843-8. Nat Immunol. 2021. PMID: 33214721 No abstract available.
19 results