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Study on Formulation, in vivo Exposure, and Passive Targeting of Intravenous Itraconazole Nanosuspensions.
Yuan Q, Wang Y, Song R, Hou X, Yu K, Zheng J, Zhang J, Pu X, Han J, Zong L. Yuan Q, et al. Front Pharmacol. 2019 Mar 28;10:225. doi: 10.3389/fphar.2019.00225. eCollection 2019. Front Pharmacol. 2019. PMID: 30983994 Free PMC article.
The level of ITZ in plasma and tissues was measured by a HPLC method. The optimized ITZ-Nanos had an average particle size of 268.1 6.5 nm and the particles were in a rectangular form. The dissolution profile of ITZ-Nanos was similar to that of commercial ITZ injections, w …
The level of ITZ in plasma and tissues was measured by a HPLC method. The optimized ITZ-Nanos had an average particle size of 268.1 6 …