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Two new naphthoate derivatives from Morinda officinalis.
Zhai HJ, Ye GH, Xue JJ, Yu JH, Zhang YY, Zhang H. Zhai HJ, et al. J Asian Nat Prod Res. 2020 Nov;22(11):1018-1023. doi: 10.1080/10286020.2019.1670648. Epub 2019 Sep 30. J Asian Nat Prod Res. 2020. PMID: 31566431
Two new naphthoate derivatives, including a symmetrical dimer (1) and a monomer (2), were separated from the roots of Morinda officinalis var. hirsuta. ...Biological evaluations revealed that the two compounds did not show inhibition against both cholinesterases AChE and B …
Two new naphthoate derivatives, including a symmetrical dimer (1) and a monomer (2), were separated from the roots of Morinda officin …
A new isoflavone glycoside from Abrus cantoniensis.
Yu MM, Wu FX, Chen WL, Kuang JW, Zhou L, Fu JJ, Sheng XF, Zou H. Yu MM, et al. J Asian Nat Prod Res. 2020 Jun;22(6):588-593. doi: 10.1080/10286020.2019.1598394. Epub 2019 Apr 13. J Asian Nat Prod Res. 2020. PMID: 30982343
A new isoflavone glycoside named as 8-O-methylrelusin-7-O-beta-D-apifuranosyl-(12)-beta-D-glucopyranoside (1), together with two known compounds, 8-O-methylrelusin-7-O-beta-D-glucopyranoside (2) and isobiflorin (3), were isolated from Abrus cantoniensis. ...
A new isoflavone glycoside named as 8-O-methylrelusin-7-O-beta-D-apifuranosyl-(12)-beta-D-glucopyranoside (1), together with two know …
Two isopentenyl resorcinols from Peperomia tetraphylla.
Lu X, Wang XX, Feng BM, Zhang Y, Yu DY, Shi LY. Lu X, et al. J Asian Nat Prod Res. 2021 Sep;23(9):851-858. doi: 10.1080/10286020.2020.1830378. Epub 2020 Oct 29. J Asian Nat Prod Res. 2021. PMID: 33118386
Their structures were determined on the basis of spectroscopic methods, especially (1)H NMR, (13)C NMR, 2D NMR, and HR-TOF-MS. Two compounds were evaluated for cytostatic activity against G(2), A 549, Hela and HCT 116 cells, but cytostatic activity of both compounds is wea …
Their structures were determined on the basis of spectroscopic methods, especially (1)H NMR, (13)C NMR, 2D NMR, and HR-TOF-MS. Two co …
Syntheses of xanthone derivatives and their bioactivity investigation.
Zhou BD, Weng ZM, Tong YG, Ma ZT, Wei RR, Li JL, Yu ZH, Xu GF, Fang YY, Ruan ZP. Zhou BD, et al. J Asian Nat Prod Res. 2021 Mar;23(3):271-283. doi: 10.1080/10286020.2020.1739024. Epub 2020 Mar 16. J Asian Nat Prod Res. 2021. PMID: 32175779
Sixteen substituted 1-hydroxy-3-methylxanthones were synthesized in one step. The yields ranged from 33 to 76%. Then, the antitumor, antioxidant, anti-tyrosinase, anti-pancreatic lipase, and antifungal activities of compounds 1-16 were evaluated. Compounds 10-12 and …
Sixteen substituted 1-hydroxy-3-methylxanthones were synthesized in one step. The yields ranged from 33 to 76%. Then, the antitumor, …
Three new antinociceptive diterpenoids from the roots of Rhododendron micranthum.
Chai B, Li Y, Yu SS. Chai B, et al. J Asian Nat Prod Res. 2020 Oct;22(10):895-904. doi: 10.1080/10286020.2020.1777545. Epub 2020 Jun 13. J Asian Nat Prod Res. 2020. PMID: 32536209
The structures of new compounds were fully determined on the basis of spectroscopic analysis, including HRESIMS, 1 D and 2 D NMR data. An acetic acid-induced writhing test in mice was proceeded to evaluate the antinociceptive activities of compounds 1-3, 5-6, 9-14 a …
The structures of new compounds were fully determined on the basis of spectroscopic analysis, including HRESIMS, 1 D and 2 D NMR data …
Bioconversion of steviol glycosides into steviol by Microbacterium barkeri.
Jiang HL, Xuan Y, Zeng Q, Yu QJ, Zhang YQ, Chen YR, Luo HB, Huang H, Xu Q. Jiang HL, et al. J Asian Nat Prod Res. 2021 Nov;23(11):1057-1067. doi: 10.1080/10286020.2020.1830379. Epub 2020 Nov 2. J Asian Nat Prod Res. 2021. PMID: 33135498
The transformation product was detected and identified as STE by HPLC/LC-MS/IR analysis. The bioconversion rate of 1% (v/v) steviol glycosides (stevioside, rebaudioside A, rebaudioside C) into STE in basic medium were 100% within 24 h, 84 h and 144 h, respectively. ...
The transformation product was detected and identified as STE by HPLC/LC-MS/IR analysis. The bioconversion rate of 1% (v/v) steviol g …
Fusapyrone A, a γ-pyrone derived from a desert Fusarium sp.
Zhen X, Mao MJ, Wang RZ, Chang SS, Xiao TM, Wu YX, Yu LY, Song YL, Chen MH, Si SY. Zhen X, et al. J Asian Nat Prod Res. 2021 May;23(5):504-511. doi: 10.1080/10286020.2020.1794857. Epub 2020 Aug 7. J Asian Nat Prod Res. 2021. PMID: 32762359
CPCC 401218, a fungus collected from the desert. The structure of 1 was characterized using various spectroscopic analyses, such as MS, IR, 1D, and 2D NMR. ...Compound 1 was found to have weak antiproliferative activity for Hela cells, with an IC(50) of 50.6 muM....
CPCC 401218, a fungus collected from the desert. The structure of 1 was characterized using various spectroscopic analyses, such as M …
Anthraquinone analogues with inhibitory activities against influenza a virus from Polygonatum odoratum.
Pang X, Zhao JY, Liu N, Chen MH, Zheng W, Zhang J, Chen XJ, Cen S, Yu LY, Ma BP. Pang X, et al. J Asian Nat Prod Res. 2021 Aug;23(8):717-723. doi: 10.1080/10286020.2020.1779707. Epub 2020 Jul 2. J Asian Nat Prod Res. 2021. PMID: 32614626
Three anthraquinone analogues (1-3) were isolated by phytochemical work on EtOAc-soluble ingredients extracted from the roots of Polygonatum odoratum. ...Specifically, 1 represents an unusual structure composed of a naphthoquinone derivative linked to an anthraquino …
Three anthraquinone analogues (1-3) were isolated by phytochemical work on EtOAc-soluble ingredients extracted from the roots of Poly …
Structural characterization and biological evaluation of chemical constituents from Ilex cornuta.
Yu SJ, Yu ZP, Wang YY, Bao J, Yuan T, Yu JH, Zhang H. Yu SJ, et al. J Asian Nat Prod Res. 2020 Apr;22(4):316-328. doi: 10.1080/10286020.2019.1570160. Epub 2019 Mar 1. J Asian Nat Prod Res. 2020. PMID: 30821481
One new ursane-type triterpenoid (1), one new ursane-type triterpenoid glycoside (2), and one new oleanane-type triterpenoid glycoside (3), along with 20 known compounds, were isolated from the leaves of Ilex cornuta. ...Our biological evaluation established that selective …
One new ursane-type triterpenoid (1), one new ursane-type triterpenoid glycoside (2), and one new oleanane-type triterpenoid glycosid …
Cycloastragenol inhibits Abeta(1-42)-induced blood-brain barrier disruption and enhances soluble Abeta efflux in vitro.
Huang MY, Yu GR. Huang MY, et al. J Asian Nat Prod Res. 2021 Jun;23(6):556-569. doi: 10.1080/10286020.2020.1786372. Epub 2020 Jul 1. J Asian Nat Prod Res. 2021. PMID: 32608254
The present results showed that CAG (10, 50, 75 muM) can alleviate oligomer Abeta(1-42) induced bEnd.3 cell apoptosis and increase tight junction scaffold proteins expression. ...
The present results showed that CAG (10, 50, 75 muM) can alleviate oligomer Abeta(1-42) induced bEnd.3 cell apoptosis and increase ti …
18 results