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Novel FGFR2::ZCCHC24 Fusion in Dysembryoplastic Neuroepithelial Tumor.
Ould Ismail AA, Parra O, Hughes EG, Green DC, Loo E, Zanazzi G, Lin CC. Ould Ismail AA, et al. J Neuropathol Exp Neurol. 2022 Nov 16;81(12):1029-1032. doi: 10.1093/jnen/nlac087. J Neuropathol Exp Neurol. 2022. PMID: 36164838 Free PMC article. No abstract available.
Establishment and verification of a prognostic model of liver cancer by RNA-binding proteins based on the TCGA database.
Apizi A, Wang L, Wusiman L, Song E, Han Y, Jia T, Zhang W. Apizi A, et al. Transl Cancer Res. 2022 Jul;11(7):1925-1937. doi: 10.21037/tcr-21-2820. Transl Cancer Res. 2022. PMID: 36249884 Free PMC article.
BACKGROUND: Globally, liver cancer is one of the most common malignant tumors and is the third leading cause of cancer deaths. ...The expression of RNA-binding proteins is related to the prognosis of liver cancer patients. METHODS: The RBP gene expression dat …
BACKGROUND: Globally, liver cancer is one of the most common malignant tumors and is the third leading cause of cancer deaths. …
Comprehensive profiling of endocrine metabolism identifies a novel signature with robust predictive value in ovarian cancer.
Yu D, Luo Y, Guo R, Ma F, Chang Y, Dang J. Yu D, et al. J Gene Med. 2024 May;26(5):e3686. doi: 10.1002/jgm.3686. J Gene Med. 2024. PMID: 38689382
Loss of enzymes or proteins can cause dysfunction of endoplasmic reticulum and Golgi apparatus and affect secretion pathways leading to a variety of human diseases, including cancer. METHODS: The single-cell RNA sequencing and single nucleotide variant principal component …
Loss of enzymes or proteins can cause dysfunction of endoplasmic reticulum and Golgi apparatus and affect secretion pathways leading to a va …
HEXIM1 as a Robust Pharmacodynamic Marker for Monitoring Target Engagement of BET Family Bromodomain Inhibitors in Tumors and Surrogate Tissues.
Lin X, Huang X, Uziel T, Hessler P, Albert DH, Roberts-Rapp LA, McDaniel KF, Kati WM, Shen Y. Lin X, et al. Mol Cancer Ther. 2017 Feb;16(2):388-396. doi: 10.1158/1535-7163.MCT-16-0475. Epub 2016 Nov 30. Mol Cancer Ther. 2017. PMID: 27903752
Candidate markers were further characterized for concentration- and time-dependent responses to the BET inhibitor ABBV-075 in vitro and in vivo HEXIM1 was found to be the only gene that exhibited robust and consistent modulation by BET inhibitors across multiple cancer ind …
Candidate markers were further characterized for concentration- and time-dependent responses to the BET inhibitor ABBV-075 in vitro and in v …
Gene regulation by antitumor miR-130b-5p in pancreatic ductal adenocarcinoma: the clinical significance of oncogenic EPS8.
Fukuhisa H, Seki N, Idichi T, Kurahara H, Yamada Y, Toda H, Kita Y, Kawasaki Y, Tanoue K, Mataki Y, Maemura K, Natsugoe S. Fukuhisa H, et al. J Hum Genet. 2019 Jun;64(6):521-534. doi: 10.1038/s10038-019-0584-6. Epub 2019 Mar 11. J Hum Genet. 2019. PMID: 30858505
The PDAC miRNA signature obtained by RNA sequencing showed that both strands of pre-miR-130b (miR-130b-5p, the passenger strand and miR-130b-3p, the guide strand) were significantly downregulated in cancer tissues. Our functional assays revealed that miR-130b-5p significan …
The PDAC miRNA signature obtained by RNA sequencing showed that both strands of pre-miR-130b (miR-130b-5p, the passenger strand and miR-130b …