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Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.
Yin H, Song CQ, Suresh S, Wu Q, Walsh S, Rhym LH, Mintzer E, Bolukbasi MF, Zhu LJ, Kauffman K, Mou H, Oberholzer A, Ding J, Kwan SY, Bogorad RL, Zatsepin T, Koteliansky V, Wolfe SA, Xue W, Langer R, Anderson DG. Yin H, et al. Among authors: zatsepin t. Nat Biotechnol. 2017 Dec;35(12):1179-1187. doi: 10.1038/nbt.4005. Epub 2017 Nov 13. Nat Biotechnol. 2017. PMID: 29131148 Free PMC article.
Ratiometric i-Motif-Based Sensor for Precise Long-Term Monitoring of pH Micro Alterations in the Nucleoplasm and Interchromatin Granules.
Petrunina NA, Shtork AS, Lukina MM, Tsvetkov VB, Khodarovich YM, Feofanov AV, Moysenovich AM, Maksimov EG, Shipunova VO, Zatsepin TS, Bogomazova AN, Shender VO, Aralov AV, Lagarkova MA, Varizhuk AM. Petrunina NA, et al. ACS Sens. 2023 Feb 24;8(2):619-629. doi: 10.1021/acssensors.2c01813. Epub 2023 Jan 20. ACS Sens. 2023. PMID: 36662613
Antitumor efficacy of multi-target in situ vaccinations with CpG oligodeoxynucleotides, anti-OX40, anti-PD1 antibodies, and aptamers.
Proskurina AS, Ruzanova VS, Ritter GS, Efremov YR, Mustafin ZS, Lashin SA, Burakova EA, Fokina AA, Zatsepin TS, Stetsenko DA, Leplina OY, Ostanin AA, Chernykh ER, Bogachev SS. Proskurina AS, et al. Among authors: zatsepin ts. J Biomed Res. 2022 Nov 28;37(3):194-212. doi: 10.7555/JBR.36.20220052. J Biomed Res. 2022. PMID: 37161885 Free PMC article.
mRNA-Based Therapeutics - Advances and Perspectives.
Sergeeva OV, Koteliansky VE, Zatsepin TS. Sergeeva OV, et al. Among authors: zatsepin ts. Biochemistry (Mosc). 2016 Jul;81(7):709-22. doi: 10.1134/S0006297916070075. Biochemistry (Mosc). 2016. PMID: 27449617 Free article. Review.
In Vivo RNAi-Mediated eIF3m Knockdown Affects Ribosome Biogenesis and Transcription but Has Limited Impact on mRNA-Specific Translation.
Smekalova EM, Gerashchenko MV, O'Connor PBF, Whittaker CA, Kauffman KJ, Fefilova AS, Zatsepin TS, Bogorad RL, Baranov PV, Langer R, Gladyshev VN, Anderson DG, Koteliansky V. Smekalova EM, et al. Mol Ther Nucleic Acids. 2020 Mar 6;19:252-266. doi: 10.1016/j.omtn.2019.11.009. Epub 2019 Nov 18. Mol Ther Nucleic Acids. 2020. PMID: 31855834 Free PMC article.
Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes.
Gerashchenko MV, Nesterchuk MV, Smekalova EM, Paulo JA, Kowalski PS, Akulich KA, Bogorad R, Dmitriev SE, Gygi S, Zatsepin T, Anderson DG, Gladyshev VN, Koteliansky VE. Gerashchenko MV, et al. Among authors: zatsepin t. Sci Rep. 2020 Sep 23;10(1):15473. doi: 10.1038/s41598-020-72399-4. Sci Rep. 2020. PMID: 32968084 Free PMC article.
141 results