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Year Number of Results
1997 4
1999 1
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2004 1
2005 1
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2009 1
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2017 1
2018 2
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2023 4
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26 results

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Zbtb14 regulates monocyte and macrophage development through inhibiting pu.1 expression in zebrafish.
Deng Y, Wang H, Liu X, Yuan H, Xu J, de Thé H, Zhou J, Zhu J. Deng Y, et al. Elife. 2022 Oct 7;11:e80760. doi: 10.7554/eLife.80760. Elife. 2022. PMID: 36205309 Free PMC article.
Mechanistically, Zbtb14 functions as a negative regulator of pu.1, and SUMOylation on a conserved lysine is essential for the repression activity of Zbtb14. Moreover, a serine to phenylalanine mutation found in an acute myeloid leukemia (AML) patient could target …
Mechanistically, Zbtb14 functions as a negative regulator of pu.1, and SUMOylation on a conserved lysine is essential for the repress …
Zbtb14 Promotes Non-Alcoholic Fatty Liver Disease-Associated Fibrosis in Gerbils via the beta-Catenin Pathway.
Chen G, Wang X, Zhu Y, Hu H, Chu X. Chen G, et al. Front Biosci (Landmark Ed). 2023 Sep 15;28(9):205. doi: 10.31083/j.fbl2809205. Front Biosci (Landmark Ed). 2023. PMID: 37796689 Free article.
Additionally, Zbtb14 regulated primary HSCs activation via the beta-catenin pathway. CONCLUSIONS: Zbtb14 regulated NAFLD-associated fibrosis via the beta-catenin pathway, for the first time, and it serves as the probable target for NAFLD therapy....
Additionally, Zbtb14 regulated primary HSCs activation via the beta-catenin pathway. CONCLUSIONS: Zbtb14 regulated NAFLD-assoc …
Integrated analysis of ATAC-seq and RNA-seq reveals the transcriptional regulation network in SLE.
Wu J, Li Y, Feng D, Yu Y, Long H, Hu Z, Lu Q, Zhao M. Wu J, et al. Int Immunopharmacol. 2023 Mar;116:109803. doi: 10.1016/j.intimp.2023.109803. Epub 2023 Feb 2. Int Immunopharmacol. 2023. PMID: 36738683
Top 5 TFs were predicted based on overlapping genes between the DAR-related genes and the DEGs: ZNF770, THAP11, ZBTB14, ETV1, POU3F1. Validation experiments indicated that the expression of TRIM25, CD163, BST2, IFIT5, IFITM3, OASL, TBX21, IL15RA and IL12RB2 was significant …
Top 5 TFs were predicted based on overlapping genes between the DAR-related genes and the DEGs: ZNF770, THAP11, ZBTB14, ETV1, POU3F1. …
Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies.
Traylor M, Persyn E, Tomppo L, Klasson S, Abedi V, Bakker MK, Torres N, Li L, Bell S, Rutten-Jacobs L, Tozer DJ, Griessenauer CJ, Zhang Y, Pedersen A, Sharma P, Jimenez-Conde J, Rundek T, Grewal RP, Lindgren A, Meschia JF, Salomaa V, Havulinna A, Kourkoulis C, Crawford K, Marini S, Mitchell BD, Kittner SJ, Rosand J, Dichgans M, Jern C, Strbian D, Fernandez-Cadenas I, Zand R, Ruigrok Y, Rost N, Lemmens R, Rothwell PM, Anderson CD, Wardlaw J, Lewis CM, Markus HS; Helsinki Stroke, Study Dutch Parelsnoer Institute-Cerebrovascular Accident (CVA) Study Group; National Institute of Neurological Disorders and Stroke (NINDS) Stroke Genetics Network; UK DNA Lacunar Stroke Study Investigators; International Stroke Genetics Consortium. Traylor M, et al. Lancet Neurol. 2021 May;20(5):351-361. doi: 10.1016/S1474-4422(21)00031-4. Epub 2021 Mar 25. Lancet Neurol. 2021. PMID: 33773637 Free PMC article.
Five loci (ICA1L-WDR12-CARF-NBEAL1, ULK4, SPI1-SLC39A13-PSMC3-RAPSN, ZCCHC14, ZBTB14-EPB41L3) were found to be associated with lacunar stroke in the European or transethnic meta-analyses. ...
Five loci (ICA1L-WDR12-CARF-NBEAL1, ULK4, SPI1-SLC39A13-PSMC3-RAPSN, ZCCHC14, ZBTB14-EPB41L3) were found to be associated with lacuna …
A genome-wide screen reveals new regulators of the 2-cell-like cell state.
Gupta N, Yakhou L, Albert JR, Azogui A, Ferry L, Kirsh O, Miura F, Battault S, Yamaguchi K, Laisné M, Domrane C, Bonhomme F, Sarkar A, Delagrange M, Ducos B, Cristofari G, Ito T, Greenberg MVC, Defossez PA. Gupta N, et al. Nat Struct Mol Biol. 2023 Aug;30(8):1105-1118. doi: 10.1038/s41594-023-01038-z. Epub 2023 Jul 24. Nat Struct Mol Biol. 2023. PMID: 37488355
Here we report the identification of four mutants that reactivate Dazl and a broader 2-cell-like signature: the E3 ubiquitin ligase adaptor SPOP, the Zinc-Finger transcription factor ZBTB14, MCM3AP, a component of the RNA processing complex TREX-2, and the lysine demethyla …
Here we report the identification of four mutants that reactivate Dazl and a broader 2-cell-like signature: the E3 ubiquitin ligase adaptor …
Zbtb21 is required for the anterior-posterior patterning of neural tissue in the early Xenopus embryo.
Takebayashi-Suzuki K, Uchida M, Suzuki A. Takebayashi-Suzuki K, et al. Biochem Biophys Res Commun. 2022 Nov 19;630:190-197. doi: 10.1016/j.bbrc.2022.09.048. Epub 2022 Sep 15. Biochem Biophys Res Commun. 2022. PMID: 36166855
Simultaneous overexpression of Zbtb21 and Zbtb14 in ectodermal explants enhances the neural-inducing activity of Zbtb14. ...Collectively, these results suggest that in cooperation with Zbtb14, Zbtb21 has a crucial function in AP patterning during early Xenopu …
Simultaneous overexpression of Zbtb21 and Zbtb14 in ectodermal explants enhances the neural-inducing activity of Zbtb14. ...Co …
Coordinated regulation of the dorsal-ventral and anterior-posterior patterning of Xenopus embryos by the BTB/POZ zinc finger protein Zbtb14.
Takebayashi-Suzuki K, Konishi H, Miyamoto T, Nagata T, Uchida M, Suzuki A. Takebayashi-Suzuki K, et al. Dev Growth Differ. 2018 Apr;60(3):158-173. doi: 10.1111/dgd.12431. Dev Growth Differ. 2018. PMID: 29664133
We show that overexpression of Zbtb14 promotes neural induction and inhibits epidermal differentiation, thereby regulating DV patterning. In addition, Zbtb14 promotes the formation of posterior neural tissue and suppresses anterior neural development. ...
We show that overexpression of Zbtb14 promotes neural induction and inhibits epidermal differentiation, thereby regulating DV pattern …
IL6 and LIF mRNA expression in skeletal muscle is regulated by AMPK and the transcription factors NFYC, ZBTB14, and SP1.
Nylén C, Aoi W, Abdelmoez AM, Lassiter DG, Lundell LS, Wallberg-Henriksson H, Näslund E, Pillon NJ, Krook A. Nylén C, et al. Am J Physiol Endocrinol Metab. 2018 Nov 1;315(5):E995-E1004. doi: 10.1152/ajpendo.00398.2017. Epub 2018 Apr 24. Am J Physiol Endocrinol Metab. 2018. PMID: 29688769 Free article.
The involvement of these transcription factors was studied after targeted gene-silencing by siRNA. siRNA silencing of the transcription factors nuclear transcription factor Y subunit c ( Nfyc), specificity protein 1 ( Sp1), and zinc finger and BTB domain containing 14 ( Zbtb14 …
The involvement of these transcription factors was studied after targeted gene-silencing by siRNA. siRNA silencing of the transcription fact …
Integration of ATAC-Seq and RNA-Seq identifies key genes and pathways involved in the neuroprotection of S-adenosylmethionine against perioperative neurocognitive disorder.
Xu F, Cong P, Lu Z, Shi L, Xiong L, Zhao G. Xu F, et al. Comput Struct Biotechnol J. 2023 Mar 3;21:1942-1954. doi: 10.1016/j.csbj.2023.03.001. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 36942104 Free PMC article.
Further motif analysis identified key transcription factors (e.g., CTCF, TFDP1, TCFL5, KLF15, ZBTB14, TFAP2E) that may participate in the neuroprotection of SAM. ...
Further motif analysis identified key transcription factors (e.g., CTCF, TFDP1, TCFL5, KLF15, ZBTB14, TFAP2E) that may participate in …
SUMOylation of zebrafish transcription factor Zbtb21 affects its transcription activity.
Fang Z, Deng Y, Wang H, Zhou J. Fang Z, et al. PeerJ. 2024 Apr 22;12:e17234. doi: 10.7717/peerj.17234. eCollection 2024. PeerJ. 2024. PMID: 38666079 Free PMC article.
SUMOylation does not affect the subcellular localization and protein stability of Zbtb21, as well as the interaction with Zbtb14 or Zbtb21. Nevertheless, luciferase reporter assays revealed that Zbtb21 is a dual-function transcription factor which exerts activation or repr …
SUMOylation does not affect the subcellular localization and protein stability of Zbtb21, as well as the interaction with Zbtb14 or Z …
26 results